| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 10 | 10 | 4 | 3 | 6.07 | .369 | 1.72 | 10.2 | 5.3 | 5.9 | 59.1 | 67 | 40 | 40 | 7 | 35 | 39 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5.10 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 10 | 10 | 4 | 3 | 4.98 | .311 | 1.32 | 6.6 | 5.3 | 7.2 | 56.0 | 41 | 31 | 31 | 4 | 33 | 45 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.20 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 10 | 10 | 5 | 3 | 3.79 | .292 | 1.21 | 8.6 | 2.3 | 6.8 | 73.2 | 70 | 32 | 31 | 11 | 19 | 55 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.32 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 8 | 7 | 5 | 2 | 4.07 | .311 | 1.34 | 9.8 | 2.4 | 3.4 | 48.2 | 52 | 22 | 22 | 7 | 13 | 18 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 5.02 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 9 | 9 | 6 | 1 | 3.19 | .307 | 1.30 | 7.8 | 4.0 | 4.7 | 67.2 | 58 | 25 | 24 | 1 | 30 | 35 | 1 | 0 | 0 | 0 | 6 | 2 | 0 | 3.58 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 27 | 0 | 4 | 0 | 1.82 | .237 | 0.89 | 6.0 | 2.3 | 8.6 | 24.2 | 16 | 5 | 5 | 0 | 6 | 23 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1.96 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 21 | 0 | 1 | 1 | 2.86 | .233 | 0.86 | 5.3 | 2.5 | 7.4 | 22.0 | 13 | 7 | 7 | 3 | 6 | 18 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.09 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 13 | 0 | 0 | 2 | 4.09 | .267 | 1.09 | 6.5 | 3.3 | 3.3 | 22.0 | 16 | 10 | 10 | 3 | 8 | 8 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 5.14 |