| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 9 | 18 | 4.76 | .297 | 1.26 | 8.5 | 2.8 | 8.0 | 204.0 | 193 | 114 | 108 | 29 | 64 | 182 | 3 | 0 | 0 | 2 | 13 | 2 | 2 | 4.03 |
| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 33 | 33 | 6 | 17 | 4.39 | .306 | 1.29 | 8.5 | 3.1 | 5.3 | 207.0 | 196 | 116 | 101 | 26 | 72 | 121 | 4 | 0 | 0 | 0 | 20 | 6 | 3 | 4.59 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 33 | 32 | 10 | 16 | 5.54 | .319 | 1.37 | 9.5 | 2.9 | 8.5 | 169.0 | 178 | 111 | 104 | 34 | 54 | 160 | 2 | 0 | 0 | 1 | 12 | 6 | 3 | 4.79 |
| SU | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 88 | 0 | 3 | 2 | 3.93 | .299 | 1.26 | 8.0 | 3.4 | 6.0 | 105.1 | 93 | 50 | 46 | 10 | 40 | 70 | 0 | 5 | 1 | 0 | 0 | 2 | 0 | 4.10 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 77 | 0 | 4 | 3 | 3.55 | .323 | 1.40 | 8.3 | 4.4 | 8.4 | 96.1 | 88 | 47 | 38 | 14 | 47 | 90 | 0 | 4 | 1 | 0 | 0 | 3 | 1 | 4.58 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 71 | 0 | 1 | 2 | 5.11 | .349 | 1.59 | 8.8 | 5.6 | 9.2 | 74.0 | 72 | 45 | 42 | 12 | 46 | 76 | 0 | 2 | 0 | 0 | 0 | 1 | 6 | 4.96 |