| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 31 | 31 | 14 | 12 | 4.01 | .308 | 1.32 | 9.0 | 2.9 | 5.1 | 224.1 | 225 | 109 | 100 | 25 | 72 | 126 | 6 | 0 | 0 | 1 | 18 | 3 | 1 | 4.33 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 30 | 30 | 10 | 11 | 5.46 | .336 | 1.48 | 9.6 | 3.8 | 5.1 | 201.0 | 214 | 126 | 122 | 23 | 84 | 114 | 2 | 0 | 0 | 1 | 9 | 7 | 11 | 4.71 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 30 | 30 | 5 | 13 | 5.85 | .351 | 1.60 | 10.6 | 3.8 | 8.0 | 163.0 | 192 | 106 | 106 | 28 | 68 | 145 | 1 | 0 | 0 | 1 | 10 | 5 | 4 | 4.80 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 30 | 29 | 11 | 9 | 5.03 | .317 | 1.38 | 9.5 | 3.0 | 4.0 | 198.2 | 208 | 117 | 111 | 24 | 66 | 89 | 4 | 0 | 0 | 2 | 13 | 3 | 7 | 4.72 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 78 | 0 | 6 | 5 | 3.00 | .299 | 1.27 | 7.7 | 3.8 | 9.0 | 96.0 | 82 | 36 | 32 | 11 | 40 | 96 | 0 | 10 | 3 | 0 | 0 | 1 | 1 | 3.77 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 68 | 0 | 8 | 2 | 3.72 | .317 | 1.39 | 7.3 | 5.4 | 9.2 | 84.2 | 68 | 39 | 35 | 4 | 50 | 86 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 3.36 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 60 | 0 | 3 | 5 | 3.24 | .302 | 1.29 | 6.3 | 5.4 | 8.8 | 77.2 | 54 | 29 | 28 | 7 | 46 | 75 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 4.06 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 47 | 0 | 5 | 1 | 2.76 | .267 | 1.07 | 5.6 | 4.2 | 9.9 | 58.2 | 36 | 19 | 18 | 3 | 27 | 64 | 0 | 4 | 2 | 0 | 0 | 1 | 3 | 2.91 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 34 | 0 | 3 | 0 | 4.14 | .291 | 1.23 | 7.0 | 4.2 | 7.7 | 41.1 | 32 | 19 | 19 | 3 | 19 | 35 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.63 |