| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 34 | 34 | 12 | 10 | 4.37 | .307 | 1.31 | 8.7 | 3.1 | 6.1 | 236.2 | 227 | 124 | 115 | 37 | 82 | 160 | 4 | 0 | 0 | 2 | 21 | 5 | 3 | 4.79 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 31 | 31 | 11 | 16 | 5.69 | .326 | 1.44 | 9.6 | 3.3 | 4.9 | 226.1 | 242 | 150 | 143 | 36 | 84 | 123 | 8 | 0 | 0 | 2 | 8 | 3 | 5 | 5.14 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 32 | 32 | 11 | 17 | 4.96 | .341 | 1.52 | 10.1 | 3.6 | 4.8 | 243.1 | 274 | 148 | 134 | 27 | 97 | 129 | 11 | 0 | 0 | 0 | 11 | 6 | 2 | 4.65 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 32 | 32 | 12 | 15 | 5.19 | .326 | 1.44 | 9.8 | 3.1 | 4.7 | 234.0 | 256 | 152 | 135 | 41 | 80 | 122 | 9 | 0 | 0 | 0 | 13 | 3 | 2 | 5.30 |
| SP | Hughes, T.Hughes, Tom # >> | 31 | 1915 | R | 64 | 32 | 31 | 9 | 11 | 5.40 | .334 | 1.48 | 10.0 | 3.3 | 4.9 | 173.1 | 193 | 111 | 104 | 22 | 63 | 94 | 0 | 0 | 0 | 0 | 9 | 5 | 6 | 4.75 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 80 | 0 | 9 | 3 | 3.61 | .266 | 1.08 | 7.1 | 2.7 | 8.4 | 94.2 | 74 | 41 | 38 | 14 | 28 | 88 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 3.99 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 74 | 0 | 3 | 2 | 3.36 | .281 | 1.15 | 6.6 | 3.9 | 8.9 | 93.2 | 68 | 37 | 35 | 7 | 40 | 92 | 0 | 9 | 0 | 0 | 0 | 2 | 0 | 3.35 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 53 | 0 | 2 | 5 | 3.58 | .336 | 1.50 | 9.0 | 4.6 | 9.0 | 55.1 | 55 | 27 | 22 | 8 | 28 | 55 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 4.47 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 29 | 0 | 4 | 2 | 4.64 | .322 | 1.42 | 10.1 | 2.7 | 10.6 | 33.0 | 37 | 21 | 17 | 4 | 10 | 39 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 3.12 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 26 | 0 | 2 | 2 | 2.93 | .270 | 1.11 | 8.1 | 2.1 | 12.0 | 30.2 | 27 | 14 | 10 | 2 | 7 | 40 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 1.90 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 26 | 0 | 0 | 1 | 2.79 | .310 | 1.34 | 7.8 | 4.3 | 7.4 | 29.0 | 25 | 11 | 9 | 1 | 14 | 24 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.24 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 6 | 2 | 2 | 1 | 4.76 | .382 | 1.85 | 11.5 | 5.7 | 7.0 | 22.2 | 28 | 14 | 12 | 2 | 14 | 17 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 4.55 |