| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 95 | 10 | 10 | 3 | 4 | 3.28 | .302 | 1.28 | 7.1 | 4.5 | 9.4 | 68.2 | 54 | 28 | 25 | 9 | 34 | 71 | 1 | 0 | 0 | 1 | 6 | 1 | 1 | 4.18 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 9 | 9 | 4 | 3 | 3.75 | .300 | 1.27 | 7.7 | 3.8 | 8.4 | 57.2 | 49 | 25 | 24 | 6 | 24 | 53 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 3.82 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 64 | 9 | 9 | 3 | 2 | 4.34 | .336 | 1.50 | 9.5 | 4.0 | 6.7 | 58.0 | 61 | 29 | 28 | 10 | 26 | 43 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 5.16 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 9 | 9 | 3 | 4 | 3.70 | .324 | 1.42 | 7.6 | 5.3 | 10.2 | 58.1 | 49 | 24 | 24 | 7 | 34 | 66 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 4.10 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 73 | 28 | 0 | 3 | 2 | 3.19 | .295 | 1.25 | 6.3 | 5.3 | 10.3 | 36.2 | 25 | 14 | 13 | 6 | 21 | 41 | 0 | 3 | 3 | 0 | 0 | 0 | 2 | 4.64 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 23 | 0 | 2 | 1 | 2.94 | .257 | 1.04 | 5.5 | 4.1 | 10.4 | 33.2 | 20 | 11 | 11 | 6 | 15 | 38 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.42 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 22 | 0 | 1 | 1 | 1.85 | .277 | 1.11 | 4.1 | 6.0 | 11.3 | 24.1 | 11 | 5 | 5 | 2 | 16 | 30 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.71 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 17 | 0 | 2 | 1 | 3.86 | .347 | 1.59 | 9.0 | 5.6 | 10.7 | 16.1 | 16 | 8 | 7 | 1 | 10 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 55 | 14 | 0 | 1 | 0 | 1.02 | .243 | 0.96 | 6.4 | 2.6 | 11.1 | 17.2 | 12 | 2 | 2 | 2 | 5 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2.94 |