| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 35 | 35 | 12 | 10 | 2.78 | .278 | 1.14 | 6.4 | 3.9 | 8.0 | 249.0 | 177 | 83 | 77 | 20 | 108 | 222 | 3 | 0 | 0 | 1 | 25 | 3 | 3 | 3.60 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 84 | 34 | 34 | 13 | 11 | 4.24 | .306 | 1.31 | 7.9 | 3.9 | 9.2 | 216.2 | 190 | 107 | 102 | 20 | 93 | 221 | 1 | 0 | 0 | 1 | 18 | 3 | 3 | 3.49 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 28 | 2017 | R | 65 | 33 | 33 | 13 | 10 | 4.00 | .302 | 1.26 | 8.8 | 2.6 | 8.0 | 227.1 | 222 | 107 | 101 | 28 | 65 | 201 | 1 | 0 | 0 | 0 | 20 | 8 | 2 | 3.80 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 54 | 31 | 31 | 13 | 12 | 3.53 | .319 | 1.37 | 7.5 | 4.8 | 8.7 | 206.2 | 172 | 81 | 81 | 25 | 111 | 199 | 0 | 0 | 0 | 0 | 22 | 7 | 2 | 4.36 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 90 | 0 | 8 | 6 | 4.18 | .306 | 1.32 | 6.3 | 5.6 | 10.5 | 114.0 | 80 | 56 | 53 | 18 | 71 | 133 | 0 | 11 | 9 | 0 | 0 | 0 | 2 | 4.59 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 85 | 0 | 6 | 3 | 2.41 | .268 | 1.09 | 5.5 | 4.4 | 10.7 | 104.2 | 63 | 28 | 28 | 11 | 51 | 124 | 0 | 12 | 6 | 0 | 0 | 1 | 6 | 3.49 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 63 | 0 | 7 | 6 | 3.35 | .313 | 1.27 | 6.0 | 5.5 | 10.3 | 75.1 | 50 | 28 | 28 | 8 | 46 | 86 | 0 | 7 | 3 | 0 | 0 | 7 | 4 | 4.21 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 49 | 0 | 4 | 3 | 3.22 | .311 | 1.35 | 7.4 | 4.9 | 10.3 | 50.1 | 41 | 19 | 18 | 4 | 27 | 57 | 0 | 5 | 3 | 0 | 0 | 0 | 2 | 3.38 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 48 | 0 | 4 | 1 | 2.29 | .262 | 1.06 | 6.1 | 3.4 | 10.4 | 63.0 | 43 | 17 | 16 | 6 | 24 | 73 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.06 |