| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 27 | 27 | 8 | 11 | 2.99 | .243 | 0.95 | 6.5 | 2.0 | 9.6 | 183.2 | 133 | 62 | 61 | 20 | 41 | 196 | 3 | 0 | 0 | 1 | 17 | 3 | 0 | 3.00 |
| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 95 | 26 | 26 | 18 | 5 | 2.43 | .267 | 1.07 | 7.0 | 2.7 | 8.3 | 200.1 | 156 | 56 | 54 | 17 | 59 | 184 | 4 | 0 | 0 | 1 | 20 | 4 | 1 | 3.21 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 26 | 26 | 13 | 11 | 3.71 | .267 | 1.08 | 8.2 | 1.5 | 6.2 | 184.1 | 168 | 77 | 76 | 24 | 31 | 126 | 8 | 0 | 0 | 2 | 17 | 2 | 1 | 3.86 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 26 | 26 | 9 | 12 | 4.71 | .296 | 1.24 | 8.7 | 2.5 | 6.1 | 162.1 | 157 | 89 | 85 | 22 | 45 | 109 | 0 | 0 | 0 | 0 | 14 | 3 | 6 | 4.31 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 75 | 25 | 25 | 14 | 6 | 3.64 | .281 | 1.15 | 8.6 | 1.8 | 8.5 | 168.0 | 160 | 68 | 68 | 18 | 34 | 158 | 1 | 0 | 0 | 0 | 16 | 3 | 2 | 3.17 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 69 | 0 | 2 | 2 | 3.39 | .277 | 1.11 | 6.7 | 3.3 | 10.9 | 87.2 | 65 | 33 | 33 | 15 | 32 | 105 | 0 | 9 | 2 | 0 | 0 | 4 | 9 | 4.07 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 63 | 0 | 7 | 3 | 3.21 | .258 | 1.02 | 7.0 | 2.2 | 9.1 | 81.1 | 63 | 29 | 29 | 5 | 20 | 82 | 0 | 12 | 2 | 0 | 0 | 2 | 0 | 2.59 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 64 | 33 | 0 | 1 | 4 | 6.39 | .340 | 1.55 | 11.3 | 2.6 | 7.8 | 31.0 | 39 | 22 | 22 | 9 | 9 | 27 | 0 | 5 | 2 | 0 | 0 | 0 | 3 | 5.90 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 62 | 15 | 0 | 3 | 1 | 1.69 | .294 | 1.25 | 6.8 | 4.5 | 7.9 | 16.0 | 12 | 3 | 3 | 0 | 8 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.75 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 61 | 15 | 0 | 0 | 0 | 4.60 | .309 | 1.28 | 8.4 | 3.6 | 10.2 | 15.2 | 14 | 8 | 8 | 5 | 6 | 17 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 6.47 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 48 | 16 | 0 | 0 | 0 | 4.08 | .264 | 1.08 | 6.4 | 3.7 | 4.2 | 17.2 | 12 | 8 | 8 | 3 | 7 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.59 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 60 | 2 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 0.0 | 2.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |