| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 91 | 36 | 36 | 10 | 14 | 3.81 | .280 | 1.14 | 7.4 | 2.8 | 8.9 | 236.0 | 195 | 100 | 100 | 40 | 74 | 234 | 2 | 0 | 0 | 0 | 23 | 6 | 5 | 4.24 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 90 | 35 | 35 | 14 | 13 | 3.81 | .282 | 1.16 | 8.2 | 2.2 | 9.0 | 233.2 | 213 | 104 | 99 | 32 | 58 | 232 | 3 | 0 | 0 | 0 | 21 | 4 | 3 | 3.59 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 83 | 33 | 33 | 13 | 11 | 2.89 | .265 | 1.06 | 7.2 | 2.4 | 6.4 | 239.2 | 191 | 80 | 77 | 26 | 64 | 170 | 5 | 0 | 0 | 1 | 25 | 4 | 0 | 3.85 |
| CL | Gossage, R.Gossage, Rich † >> | 30 | 1981 | R | 88 | 63 | 0 | 6 | 7 | 2.37 | .257 | 1.01 | 5.2 | 3.9 | 8.6 | 76.0 | 44 | 20 | 20 | 5 | 33 | 73 | 0 | 33 | 5 | 0 | 0 | 2 | 2 | 3.32 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 80 | 0 | 4 | 2 | 2.84 | .288 | 1.17 | 5.6 | 5.0 | 9.0 | 85.2 | 53 | 28 | 27 | 12 | 47 | 85 | 0 | 5 | 0 | 0 | 0 | 4 | 0 | 4.64 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 46 | 0 | 5 | 2 | 2.09 | .225 | 0.83 | 4.4 | 3.2 | 8.5 | 51.2 | 25 | 12 | 12 | 2 | 18 | 48 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 2.80 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 30 | 0 | 1 | 2 | 2.84 | .252 | 1.01 | 7.8 | 1.5 | 9.3 | 31.2 | 27 | 10 | 10 | 5 | 5 | 32 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.52 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 1 | 0 | 0 | 0 | 3.86 | .333 | 1.50 | 11.3 | 4.5 | 11.3 | 4.2 | 5 | 2 | 2 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.25 |