| SP | deGrom, J.deGrom, Jacob # $ >> | 33 | 2021 | R | 100 | 31 | 31 | 13 | 7 | 3.21 | .260 | 1.03 | 7.2 | 2.1 | 10.0 | 207.1 | 166 | 77 | 74 | 25 | 48 | 231 | 0 | 0 | 0 | 0 | 21 | 5 | 0 | 3.11 |
| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 94 | 30 | 30 | 14 | 9 | 3.54 | .272 | 1.09 | 7.4 | 2.4 | 5.3 | 221.1 | 182 | 90 | 87 | 28 | 60 | 130 | 7 | 0 | 0 | 2 | 17 | 6 | 4 | 4.37 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 29 | 29 | 15 | 10 | 5.10 | .312 | 1.36 | 8.7 | 3.5 | 9.0 | 178.1 | 173 | 103 | 101 | 29 | 70 | 178 | 2 | 0 | 0 | 2 | 13 | 0 | 1 | 4.30 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 29 | 29 | 9 | 10 | 4.93 | .309 | 1.32 | 9.5 | 2.4 | 7.3 | 184.1 | 195 | 103 | 101 | 15 | 49 | 149 | 5 | 0 | 0 | 1 | 14 | 3 | 7 | 3.29 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 81 | 0 | 8 | 5 | 4.82 | .311 | 1.34 | 8.3 | 3.8 | 9.2 | 108.1 | 99 | 59 | 58 | 11 | 46 | 110 | 0 | 10 | 4 | 0 | 0 | 2 | 3 | 3.62 |
| RP | Miller, A.Miller, Andrew $ >> | 31 | 2016 | L | 91 | 61 | 0 | 3 | 5 | 3.24 | .260 | 1.05 | 8.0 | 1.6 | 8.2 | 80.2 | 71 | 31 | 29 | 9 | 14 | 73 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 3.16 |
| RP | Betances, D.Betances, Dellin † >> | 26 | 2014 | R | 93 | 57 | 0 | 5 | 6 | 3.36 | .282 | 1.13 | 6.9 | 3.4 | 8.6 | 69.2 | 53 | 27 | 26 | 6 | 26 | 66 | 0 | 10 | 1 | 0 | 0 | 3 | 2 | 3.48 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 38 | 0 | 0 | 2 | 4.71 | .351 | 1.62 | 12.0 | 2.8 | 6.5 | 36.1 | 48 | 19 | 19 | 6 | 11 | 26 | 0 | 7 | 1 | 0 | 0 | 0 | 2 | 4.64 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 25 | 0 | 1 | 0 | 1.44 | .265 | 1.08 | 5.4 | 4.3 | 7.9 | 25.0 | 15 | 5 | 4 | 1 | 12 | 22 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.20 |