| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 10 | 18 | 4.60 | .316 | 1.37 | 9.1 | 3.2 | 8.7 | 219.0 | 222 | 125 | 112 | 26 | 78 | 212 | 2 | 0 | 0 | 1 | 14 | 4 | 5 | 3.73 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 33 | 33 | 13 | 16 | 3.75 | .288 | 1.19 | 8.3 | 2.4 | 4.9 | 237.2 | 218 | 108 | 99 | 18 | 64 | 130 | 8 | 0 | 0 | 3 | 17 | 6 | 6 | 3.78 |
| SP | Gibson, B.Gibson, Bob † # >> | 33 | 1968 | R | 92 | 32 | 32 | 19 | 12 | 3.49 | .289 | 1.20 | 8.0 | 2.8 | 5.3 | 255.1 | 228 | 113 | 99 | 16 | 78 | 151 | 21 | 0 | 0 | 3 | 21 | 5 | 3 | 3.61 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 32 | 32 | 9 | 12 | 4.57 | .326 | 1.41 | 9.0 | 3.7 | 8.3 | 214.2 | 215 | 121 | 109 | 19 | 88 | 198 | 3 | 0 | 0 | 3 | 15 | 8 | 2 | 3.65 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 81 | 0 | 4 | 2 | 2.63 | .277 | 1.12 | 7.1 | 2.9 | 10.2 | 92.1 | 73 | 30 | 27 | 9 | 30 | 104 | 0 | 8 | 1 | 0 | 0 | 3 | 1 | 3.09 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 67 | 0 | 2 | 5 | 3.44 | .331 | 1.44 | 8.7 | 4.4 | 10.4 | 70.2 | 68 | 30 | 27 | 9 | 34 | 81 | 0 | 13 | 2 | 0 | 0 | 3 | 0 | 3.94 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 44 | 0 | 1 | 4 | 2.65 | .261 | 1.04 | 5.8 | 3.6 | 8.7 | 57.2 | 37 | 24 | 17 | 3 | 23 | 55 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 3.02 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 26 | 0 | 3 | 2 | 2.70 | .344 | 1.58 | 7.6 | 6.9 | 9.7 | 26.2 | 22 | 12 | 8 | 2 | 20 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.15 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 17 | 0 | 1 | 0 | 5.82 | .370 | 1.76 | 11.6 | 4.2 | 8.5 | 17.0 | 22 | 11 | 11 | 4 | 8 | 16 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 5.59 |