| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 23 | 23 | 8 | 7 | 4.60 | .300 | 1.27 | 8.7 | 2.8 | 9.5 | 133.0 | 128 | 68 | 68 | 14 | 41 | 141 | 1 | 0 | 0 | 1 | 12 | 2 | 0 | 3.22 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 23 | 23 | 9 | 10 | 4.78 | .292 | 1.22 | 8.6 | 2.4 | 4.3 | 145.0 | 139 | 79 | 77 | 15 | 38 | 69 | 3 | 0 | 0 | 1 | 10 | 2 | 0 | 4.22 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 20 | 20 | 6 | 9 | 4.20 | .304 | 1.30 | 8.0 | 3.8 | 7.3 | 124.1 | 110 | 60 | 58 | 9 | 52 | 100 | 0 | 0 | 0 | 0 | 9 | 1 | 1 | 3.61 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 22 | 21 | 5 | 9 | 3.97 | .329 | 1.45 | 8.6 | 4.5 | 7.5 | 127.0 | 121 | 60 | 56 | 8 | 63 | 106 | 0 | 0 | 0 | 0 | 11 | 3 | 3 | 3.71 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 69 | 0 | 5 | 6 | 2.64 | .266 | 1.08 | 6.4 | 3.3 | 4.5 | 92.0 | 65 | 34 | 27 | 11 | 34 | 46 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.70 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 57 | 0 | 1 | 7 | 4.18 | .300 | 1.25 | 8.3 | 3.1 | 7.0 | 64.2 | 59 | 32 | 30 | 9 | 22 | 50 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 4.39 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 42 | 0 | 2 | 2 | 4.57 | .364 | 1.65 | 7.8 | 7.2 | 8.2 | 45.1 | 39 | 23 | 23 | 7 | 36 | 41 | 0 | 2 | 1 | 0 | 0 | 3 | 1 | 5.80 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 40 | 0 | 3 | 1 | 2.64 | .249 | 0.99 | 5.6 | 3.4 | 6.0 | 61.1 | 38 | 20 | 18 | 5 | 23 | 41 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.85 |
| CL | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 52 | 0 | 2 | 4 | 2.37 | .266 | 1.09 | 4.7 | 5.1 | 8.7 | 57.0 | 30 | 17 | 15 | 6 | 32 | 55 | 0 | 21 | 3 | 0 | 0 | 0 | 1 | 4.12 |