| SP | Clevinger, M.Clevinger, Mike >> | 28 | 2019 | R | 67 | 29 | 25 | 9 | 10 | 3.53 | .302 | 1.27 | 8.1 | 3.4 | 10.4 | 165.2 | 148 | 67 | 65 | 19 | 63 | 190 | 0 | 0 | 0 | 0 | 15 | 4 | 0 | 3.41 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 67 | 28 | 20 | 8 | 9 | 5.21 | .324 | 1.41 | 9.2 | 3.6 | 10.0 | 169.1 | 172 | 98 | 98 | 30 | 67 | 187 | 0 | 0 | 0 | 0 | 9 | 4 | 5 | 4.36 |
| SP | Peralta, F.Peralta, Freddy $$ >> | 25 | 2021 | R | 95 | 37 | 37 | 8 | 16 | 3.47 | .292 | 1.21 | 6.6 | 4.3 | 9.6 | 212.2 | 155 | 83 | 82 | 28 | 102 | 225 | 0 | 0 | 0 | 0 | 14 | 6 | 1 | 4.12 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 88 | 30 | 29 | 10 | 14 | 4.17 | .290 | 1.21 | 7.8 | 3.1 | 9.4 | 203.0 | 176 | 102 | 94 | 20 | 69 | 212 | 4 | 0 | 0 | 3 | 16 | 4 | 7 | 3.27 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 33 | 0 | 0 | 1 | 3.19 | .311 | 1.29 | 6.7 | 4.9 | 4.1 | 31.0 | 23 | 11 | 11 | 1 | 17 | 14 | 0 | 4 | 1 | 0 | 0 | 2 | 2 | 4.35 |
| RP | Holton, T.Holton, Tyler >> | 28 | 2024 | L | 68 | 34 | 0 | 4 | 2 | 2.04 | .264 | 1.08 | 6.7 | 3.1 | 8.2 | 35.1 | 26 | 9 | 8 | 0 | 12 | 32 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 2.20 |
| RP | Robertson, D.Robertson, David >> | 32 | 2017 | R | 81 | 43 | 0 | 3 | 4 | 4.50 | .309 | 1.32 | 7.4 | 4.5 | 10.8 | 44.0 | 36 | 24 | 22 | 3 | 22 | 53 | 0 | 6 | 2 | 0 | 0 | 1 | 4 | 3.05 |
| RP | Giles, K.Giles, Ken $$ >> | 23 | 2014 | R | 83 | 77 | 0 | 6 | 3 | 1.75 | .236 | 0.92 | 4.8 | 3.5 | 10.6 | 92.2 | 49 | 19 | 18 | 4 | 36 | 108 | 0 | 15 | 3 | 0 | 0 | 1 | 1 | 2.42 |
| SP | Manoah, A.Manoah, Alek # $$ >> | 24 | 2022 | R | 79 | 33 | 30 | 13 | 7 | 3.80 | .277 | 1.13 | 7.3 | 2.9 | 7.5 | 217.2 | 176 | 95 | 92 | 30 | 71 | 181 | 0 | 0 | 0 | 0 | 18 | 3 | 5 | 4.15 |
| SP | Harvey, M.Harvey, Matt † $$ >> | 24 | 2013 | R | 82 | 31 | 31 | 15 | 12 | 3.52 | .289 | 1.17 | 7.8 | 2.7 | 9.8 | 212.0 | 184 | 87 | 83 | 17 | 64 | 230 | 4 | 0 | 0 | 0 | 20 | 11 | 2 | 2.93 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 90 | 83 | 0 | 6 | 6 | 3.45 | .295 | 1.25 | 7.1 | 4.2 | 10.4 | 104.1 | 82 | 42 | 40 | 14 | 48 | 120 | 0 | 11 | 8 | 0 | 0 | 1 | 0 | 3.86 |