| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 38 | 38 | 14 | 13 | 4.30 | .308 | 1.30 | 8.7 | 3.0 | 9.9 | 234.2 | 225 | 114 | 112 | 36 | 79 | 257 | 2 | 0 | 0 | 0 | 20 | 10 | 4 | 3.94 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 98 | 39 | 39 | 12 | 16 | 4.12 | .303 | 1.27 | 8.5 | 2.9 | 10.3 | 238.1 | 225 | 114 | 109 | 34 | 78 | 273 | 4 | 0 | 0 | 3 | 24 | 8 | 6 | 3.65 |
| SP | Gallen, Z.Gallen, Zac # >> | 26 | 2022 | R | 92 | 39 | 38 | 15 | 18 | 4.49 | .307 | 1.28 | 8.6 | 3.0 | 9.9 | 222.2 | 211 | 114 | 111 | 30 | 75 | 244 | 0 | 0 | 0 | 0 | 21 | 10 | 3 | 3.71 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 92 | 36 | 36 | 17 | 10 | 3.27 | .272 | 1.08 | 7.1 | 2.7 | 7.7 | 245.0 | 192 | 95 | 89 | 22 | 73 | 210 | 6 | 0 | 0 | 4 | 24 | 10 | 5 | 3.47 |
| SP | Bauer, T.Bauer, Trevor >> | 30 | 2021 | R | 83 | 23 | 18 | 10 | 2 | 3.39 | .286 | 1.18 | 7.1 | 3.5 | 10.7 | 114.0 | 90 | 45 | 43 | 10 | 44 | 135 | 0 | 1 | 0 | 0 | 11 | 3 | 3 | 3.01 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 99 | 98 | 0 | 6 | 3 | 3.73 | .301 | 1.25 | 8.1 | 3.2 | 11.7 | 120.2 | 108 | 51 | 50 | 11 | 43 | 156 | 0 | 12 | 5 | 0 | 0 | 5 | 1 | 2.79 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 98 | 84 | 0 | 4 | 9 | 3.43 | .302 | 1.28 | 6.7 | 4.9 | 11.3 | 89.1 | 66 | 35 | 34 | 12 | 48 | 112 | 0 | 14 | 2 | 0 | 0 | 2 | 13 | 3.92 |
| RP | Pagan, E.Pagan, Emilio # >> | 28 | 2019 | R | 71 | 51 | 0 | 0 | 4 | 5.94 | .327 | 1.44 | 10.6 | 2.3 | 10.8 | 50.0 | 59 | 35 | 33 | 7 | 13 | 60 | 0 | 6 | 1 | 0 | 0 | 1 | 3 | 3.26 |
| RP | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 58 | 38 | 0 | 3 | 0 | 3.50 | .265 | 1.06 | 7.0 | 2.5 | 7.2 | 46.1 | 36 | 20 | 18 | 7 | 13 | 37 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.28 |
| SP | Corbin, P.Corbin, Patrick >> | 28 | 2018 | L | 60 | 25 | 0 | 5 | 4 | 5.29 | .342 | 1.50 | 9.7 | 3.8 | 10.2 | 102.0 | 110 | 60 | 60 | 15 | 43 | 116 | 0 | 0 | 0 | 0 | 0 | 6 | 4 | 4.08 |