| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 21 | 21 | 13 | 3 | 3.10 | .256 | 0.99 | 7.4 | 1.6 | 9.3 | 168.1 | 138 | 58 | 58 | 22 | 29 | 173 | 6 | 0 | 0 | 1 | 15 | 7 | 4 | 3.29 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 20 | 20 | 4 | 13 | 4.32 | .316 | 1.37 | 9.1 | 3.2 | 9.1 | 135.1 | 137 | 67 | 65 | 17 | 48 | 136 | 1 | 0 | 0 | 1 | 11 | 3 | 2 | 3.76 |
| SP | Hernandez, F.Hernandez, Felix † >> | 28 | 2014 | R | 88 | 20 | 20 | 11 | 6 | 4.14 | .305 | 1.28 | 8.4 | 3.1 | 9.1 | 137.0 | 128 | 66 | 63 | 21 | 47 | 139 | 3 | 0 | 0 | 1 | 11 | 5 | 1 | 4.10 |
| SP | Shields, J.Shields, James # >> | 30 | 2011 | R | 63 | 19 | 19 | 13 | 2 | 4.10 | .309 | 1.29 | 9.3 | 2.3 | 8.1 | 142.2 | 147 | 70 | 65 | 19 | 37 | 128 | 3 | 0 | 0 | 0 | 9 | 7 | 0 | 3.87 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 49 | 0 | 5 | 2 | 3.76 | .272 | 1.06 | 7.1 | 2.4 | 10.9 | 67.0 | 53 | 28 | 28 | 13 | 18 | 81 | 0 | 7 | 3 | 0 | 0 | 4 | 1 | 4.09 |
| RP | Petit, Y.Petit, Yusmeiro >> | 35 | 2019 | R | 70 | 19 | 0 | 1 | 0 | 2.86 | .320 | 1.36 | 9.4 | 2.9 | 6.1 | 22.0 | 23 | 7 | 7 | 2 | 7 | 15 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 3.91 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 64 | 24 | 0 | 0 | 0 | 2.81 | .222 | 0.82 | 4.3 | 3.2 | 10.1 | 25.2 | 12 | 8 | 8 | 4 | 9 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.04 |
| RP | Melancon, M.Melancon, Mark >> | 29 | 2014 | R | 47 | 5 | 0 | 0 | 0 | 3.18 | .320 | 1.41 | 10.8 | 3.6 | 14.4 | 5.2 | 6 | 2 | 2 | 1 | 2 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.60 |