| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 9 | 9 | 4 | 4 | 5.08 | .303 | 1.27 | 8.9 | 2.6 | 7.1 | 62.0 | 61 | 35 | 35 | 6 | 18 | 49 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 3.65 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 96 | 9 | 9 | 7 | 2 | 3.03 | .263 | 1.07 | 7.5 | 2.1 | 5.6 | 68.1 | 57 | 26 | 23 | 9 | 16 | 42 | 2 | 0 | 0 | 1 | 8 | 0 | 0 | 4.19 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 95 | 8 | 8 | 1 | 2 | 6.75 | .325 | 1.43 | 9.3 | 3.6 | 8.0 | 53.1 | 55 | 44 | 40 | 13 | 21 | 47 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 5.66 |
| SP | Brown, M.Brown, Mordecai >> | 33 | 1909 | R | 90 | 8 | 8 | 6 | 1 | 4.66 | .297 | 1.21 | 8.8 | 2.1 | 5.6 | 56.0 | 55 | 30 | 29 | 11 | 13 | 35 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 5.16 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 79 | 8 | 8 | 4 | 2 | 5.65 | .320 | 1.37 | 10.2 | 2.1 | 9.5 | 51.0 | 58 | 32 | 32 | 7 | 12 | 54 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 3.49 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 100 | 16 | 0 | 0 | 1 | 1.20 | .182 | 0.67 | 5.4 | 0.6 | 9.6 | 15.0 | 9 | 2 | 2 | 2 | 1 | 16 | 0 | 13 | 0 | 0 | 0 | 0 | 0 | 2.80 |
| SU | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 98 | 17 | 0 | 0 | 2 | 3.32 | .269 | 1.11 | 8.5 | 1.4 | 8.5 | 19.0 | 18 | 9 | 7 | 3 | 3 | 18 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 3.63 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 94 | 18 | 0 | 3 | 1 | 3.15 | .241 | 0.95 | 7.2 | 1.4 | 9.5 | 20.0 | 16 | 7 | 7 | 4 | 3 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.95 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 12 | 0 | 0 | 2 | 3.68 | .290 | 1.23 | 10.3 | 1.3 | 8.4 | 14.2 | 16 | 6 | 6 | 2 | 2 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Jackson, M.Jackson, Mike >> | 34 | 1998 | R | 78 | 8 | 0 | 0 | 0 | 4.32 | .390 | 1.92 | 10.1 | 7.9 | 9.0 | 8.1 | 9 | 7 | 4 | 0 | 7 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.63 |