| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 9 | 9 | 5 | 2 | 2.40 | .265 | 1.08 | 6.8 | 3.0 | 9.5 | 60.0 | 45 | 17 | 16 | 6 | 20 | 63 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 3.20 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 76 | 9 | 9 | 2 | 5 | 6.83 | .346 | 1.55 | 11.9 | 2.0 | 5.1 | 58.0 | 77 | 53 | 44 | 15 | 13 | 33 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 6.00 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 9 | 9 | 3 | 4 | 5.68 | .338 | 1.53 | 10.7 | 3.3 | 5.9 | 58.2 | 69 | 40 | 37 | 10 | 21 | 38 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 5.02 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 9 | 9 | 3 | 1 | 5.75 | .362 | 1.68 | 10.4 | 4.9 | 3.2 | 51.2 | 59 | 33 | 33 | 4 | 28 | 18 | 1 | 0 | 0 | 0 | 3 | 1 | 1 | 5.02 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 23 | 0 | 2 | 0 | 2.08 | .261 | 1.06 | 6.9 | 3.0 | 12.0 | 21.2 | 16 | 5 | 5 | 0 | 7 | 28 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 1.33 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 29 | 0 | 2 | 1 | 5.06 | .319 | 1.36 | 7.7 | 4.7 | 9.4 | 21.1 | 18 | 12 | 12 | 3 | 11 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.48 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 18 | 0 | 3 | 1 | 4.32 | .286 | 1.16 | 8.3 | 2.2 | 5.0 | 25.0 | 23 | 12 | 12 | 4 | 6 | 14 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.80 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 15 | 0 | 1 | 2 | 6.75 | .314 | 1.38 | 10.1 | 2.3 | 11.3 | 16.0 | 18 | 12 | 12 | 0 | 4 | 20 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 1.25 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 2 | 0 | 0 | 0 | 10.80 | .444 | 2.40 | 36.0 | 0.0 | 18.0 | 1.2 | 4 | 2 | 2 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | -1.00 |