| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 4 | 4 | 3 | 1 | 2.05 | .275 | 1.14 | 6.2 | 4.2 | 13.2 | 26.1 | 18 | 6 | 6 | 2 | 12 | 38 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2.46 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 4 | 4 | 1 | 3 | 5.18 | .330 | 1.48 | 10.5 | 3.0 | 8.6 | 24.1 | 28 | 14 | 14 | 5 | 8 | 23 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 4.79 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 4 | 4 | 3 | 0 | 2.25 | .256 | 1.00 | 7.0 | 2.0 | 2.8 | 32.0 | 25 | 8 | 8 | 1 | 7 | 10 | 1 | 0 | 0 | 0 | 3 | 1 | 1 | 3.53 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 4 | 4 | 1 | 1 | 4.00 | .357 | 1.67 | 10.0 | 5.0 | 4.0 | 27.0 | 30 | 15 | 12 | 2 | 15 | 12 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4.74 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 4 | 4 | 2 | 0 | 6.29 | .387 | 1.85 | 12.4 | 4.5 | 6.4 | 24.1 | 33 | 17 | 17 | 1 | 12 | 17 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 3.75 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 10 | 0 | 0 | 0 | 3.14 | .283 | 1.19 | 6.4 | 4.5 | 7.7 | 14.1 | 10 | 5 | 5 | 2 | 7 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.64 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 12 | 0 | 1 | 0 | 3.46 | .291 | 1.23 | 7.6 | 3.5 | 8.3 | 13.0 | 11 | 9 | 5 | 0 | 5 | 12 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.31 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 7 | 0 | 0 | 0 | 3.86 | .364 | 1.71 | 11.6 | 3.9 | 10.3 | 7.0 | 9 | 3 | 3 | 1 | 3 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.86 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 2 | 0 | 1 | 0 | 2.08 | .350 | 1.62 | 9.0 | 6.8 | 9.0 | 4.1 | 4 | 1 | 1 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.25 |