| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 16 | 16 | 7 | 3 | 3.10 | .288 | 1.22 | 8.5 | 2.5 | 9.3 | 98.2 | 93 | 40 | 34 | 10 | 27 | 101 | 0 | 0 | 0 | 0 | 10 | 0 | 0 | 3.09 |
| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 16 | 16 | 6 | 4 | 2.78 | .271 | 1.08 | 6.8 | 2.9 | 7.6 | 100.1 | 76 | 34 | 31 | 13 | 32 | 84 | 0 | 0 | 0 | 0 | 10 | 4 | 0 | 4.09 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 16 | 16 | 7 | 6 | 4.19 | .302 | 1.29 | 8.1 | 3.6 | 5.4 | 81.2 | 73 | 40 | 38 | 11 | 32 | 49 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 4.78 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 16 | 16 | 4 | 3 | 5.50 | .318 | 1.38 | 7.9 | 4.7 | 7.6 | 73.2 | 64 | 48 | 45 | 8 | 38 | 62 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 4.33 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 39 | 0 | 1 | 1 | 4.95 | .339 | 1.49 | 8.5 | 5.0 | 11.5 | 36.1 | 34 | 20 | 20 | 7 | 20 | 46 | 0 | 2 | 1 | 0 | 0 | 2 | 5 | 4.81 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 48 | 0 | 2 | 1 | 3.32 | .265 | 1.05 | 7.1 | 2.4 | 9.9 | 38.0 | 30 | 15 | 14 | 6 | 10 | 42 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.71 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 50 | 35 | 0 | 0 | 2 | 4.43 | .351 | 1.62 | 10.8 | 4.1 | 4.5 | 20.1 | 24 | 10 | 10 | 2 | 9 | 10 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 4.65 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 42 | 0 | 3 | 1 | 3.42 | .325 | 1.44 | 8.0 | 5.2 | 6.6 | 26.1 | 23 | 10 | 10 | 3 | 15 | 19 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 4.77 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 31 | 0 | 3 | 3 | 6.28 | .344 | 1.57 | 11.6 | 2.9 | 7.4 | 28.2 | 36 | 21 | 20 | 5 | 9 | 23 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 4.64 |