| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 36 | 36 | 16 | 13 | 3.26 | .274 | 1.09 | 7.3 | 2.6 | 10.0 | 256.2 | 208 | 94 | 93 | 31 | 73 | 284 | 4 | 0 | 0 | 2 | 24 | 10 | 2 | 3.33 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 89 | 34 | 34 | 11 | 13 | 4.06 | .324 | 1.41 | 9.5 | 3.2 | 7.0 | 250.2 | 263 | 130 | 113 | 33 | 90 | 194 | 3 | 0 | 0 | 1 | 17 | 7 | 5 | 4.33 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 84 | 33 | 33 | 16 | 7 | 4.29 | .305 | 1.30 | 8.9 | 2.8 | 7.1 | 207.2 | 205 | 105 | 99 | 36 | 65 | 164 | 0 | 0 | 0 | 0 | 24 | 4 | 3 | 4.68 |
| SP | Clevinger, M.Clevinger, Mike >> | 28 | 2019 | R | 75 | 33 | 33 | 16 | 8 | 4.14 | .302 | 1.29 | 8.6 | 3.1 | 9.7 | 202.1 | 192 | 94 | 93 | 31 | 69 | 218 | 1 | 0 | 0 | 1 | 21 | 2 | 0 | 3.89 |
| SP | Keuchel, D.Keuchel, Dallas † >> | 27 | 2015 | L | 69 | 31 | 31 | 12 | 8 | 4.63 | .317 | 1.38 | 9.8 | 2.6 | 7.9 | 221.2 | 241 | 121 | 114 | 32 | 64 | 194 | 4 | 0 | 0 | 1 | 14 | 3 | 5 | 4.04 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 92 | 0 | 10 | 7 | 2.55 | .253 | 0.99 | 6.8 | 2.1 | 9.1 | 127.0 | 96 | 39 | 36 | 13 | 30 | 129 | 0 | 12 | 7 | 0 | 0 | 3 | 2 | 3.08 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 89 | 81 | 0 | 7 | 3 | 3.24 | .267 | 1.06 | 5.7 | 3.9 | 10.4 | 86.0 | 54 | 34 | 31 | 9 | 37 | 99 | 0 | 19 | 3 | 0 | 0 | 3 | 3 | 3.45 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 88 | 45 | 0 | 5 | 4 | 2.72 | .249 | 0.99 | 5.9 | 3.1 | 10.4 | 56.1 | 37 | 17 | 17 | 8 | 19 | 65 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 3.55 |
| RP | Robertson, D.Robertson, David >> | 32 | 2017 | R | 86 | 31 | 0 | 3 | 4 | 3.27 | .313 | 1.33 | 8.7 | 3.3 | 11.2 | 33.0 | 32 | 15 | 12 | 2 | 12 | 41 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 2.48 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 81 | 26 | 0 | 1 | 1 | 5.64 | .350 | 1.61 | 10.2 | 4.5 | 9.4 | 22.1 | 25 | 14 | 14 | 5 | 11 | 23 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 5.36 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 76 | 27 | 0 | 0 | 2 | 4.11 | .271 | 1.09 | 8.0 | 1.8 | 11.1 | 35.0 | 31 | 17 | 16 | 9 | 7 | 43 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.57 |
| SP | Syndergaard, N.Syndergaard, Noah >> | 22 | 2015 | R | 58 | 3 | 0 | 0 | 0 | 2.08 | .188 | 0.69 | 6.8 | 0.0 | 6.8 | 4.1 | 3 | 1 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |