| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 36 | 36 | 11 | 19 | 4.60 | .305 | 1.27 | 9.3 | 2.2 | 8.3 | 262.0 | 271 | 140 | 134 | 38 | 63 | 241 | 6 | 0 | 0 | 1 | 16 | 11 | 11 | 3.89 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 35 | 35 | 10 | 20 | 4.36 | .300 | 1.28 | 8.6 | 2.9 | 8.4 | 247.2 | 237 | 123 | 120 | 25 | 79 | 231 | 7 | 0 | 0 | 1 | 18 | 3 | 2 | 3.44 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 33 | 33 | 13 | 12 | 4.21 | .305 | 1.29 | 8.4 | 3.2 | 5.5 | 239.1 | 223 | 125 | 112 | 30 | 85 | 146 | 1 | 0 | 0 | 0 | 17 | 7 | 2 | 4.56 |
| SP | Walsh, E.Walsh, Ed † # >> | 29 | 1910 | R | 93 | 33 | 33 | 17 | 10 | 3.11 | .266 | 1.06 | 7.4 | 2.2 | 4.5 | 275.1 | 226 | 96 | 95 | 22 | 67 | 138 | 19 | 0 | 0 | 4 | 22 | 7 | 6 | 3.84 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 31 | 31 | 11 | 7 | 4.86 | .315 | 1.37 | 9.4 | 2.9 | 5.0 | 161.0 | 168 | 96 | 87 | 20 | 52 | 90 | 0 | 0 | 0 | 0 | 12 | 2 | 5 | 4.50 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 97 | 0 | 12 | 1 | 3.63 | .301 | 1.27 | 7.8 | 3.7 | 7.2 | 86.2 | 75 | 37 | 35 | 11 | 35 | 69 | 0 | 5 | 5 | 0 | 0 | 2 | 3 | 4.35 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 92 | 0 | 3 | 2 | 2.23 | .235 | 0.89 | 5.1 | 3.0 | 9.8 | 60.2 | 34 | 17 | 15 | 4 | 20 | 65 | 0 | 6 | 2 | 0 | 0 | 2 | 3 | 2.80 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 39 | 0 | 3 | 1 | 4.24 | .297 | 1.26 | 8.6 | 2.9 | 9.9 | 40.1 | 38 | 20 | 19 | 7 | 13 | 44 | 0 | 11 | 2 | 0 | 0 | 0 | 4 | 4.05 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 29 | 0 | 2 | 2 | 5.65 | .306 | 1.33 | 8.7 | 3.5 | 9.0 | 28.2 | 27 | 18 | 18 | 7 | 11 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.43 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 32 | 0 | 0 | 0 | 4.01 | .369 | 1.75 | 10.4 | 5.7 | 9.5 | 33.2 | 38 | 16 | 15 | 5 | 21 | 35 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.76 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 6 | 0 | 3 | 0 | 0.00 | .267 | 1.09 | 3.9 | 6.4 | 1.3 | 7.1 | 3 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.86 |