| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 35 | 35 | 17 | 9 | 2.91 | .277 | 1.10 | 5.9 | 4.1 | 7.1 | 222.1 | 145 | 73 | 72 | 11 | 100 | 175 | 1 | 0 | 0 | 1 | 27 | 11 | 4 | 3.57 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 32 | 32 | 18 | 11 | 3.41 | .254 | 1.01 | 7.4 | 1.7 | 5.4 | 213.2 | 175 | 85 | 81 | 18 | 40 | 127 | 5 | 0 | 0 | 2 | 20 | 3 | 6 | 3.51 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 31 | 31 | 13 | 5 | 3.69 | .271 | 1.11 | 7.9 | 2.1 | 8.2 | 197.2 | 173 | 84 | 81 | 24 | 46 | 180 | 1 | 0 | 0 | 0 | 19 | 2 | 3 | 3.49 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 62 | 0 | 7 | 2 | 3.27 | .269 | 1.10 | 6.1 | 3.9 | 7.9 | 71.2 | 48 | 26 | 26 | 11 | 31 | 62 | 0 | 2 | 2 | 0 | 0 | 0 | 11 | 4.58 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 90 | 0 | 3 | 3 | 4.32 | .290 | 1.19 | 6.4 | 4.3 | 8.5 | 102.0 | 72 | 52 | 49 | 10 | 49 | 96 | 0 | 5 | 6 | 0 | 0 | 4 | 6 | 3.95 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 77 | 0 | 9 | 2 | 3.30 | .313 | 1.34 | 6.9 | 5.1 | 9.9 | 79.0 | 61 | 31 | 29 | 7 | 45 | 87 | 0 | 1 | 3 | 0 | 0 | 2 | 6 | 3.73 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 50 | 0 | 2 | 3 | 2.70 | .271 | 1.10 | 4.4 | 5.5 | 6.4 | 70.0 | 34 | 21 | 21 | 7 | 43 | 50 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 4.76 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 32 | 31 | 15 | 9 | 3.99 | .315 | 1.36 | 7.3 | 5.0 | 3.9 | 196.0 | 159 | 105 | 87 | 19 | 108 | 84 | 1 | 1 | 0 | 1 | 18 | 3 | 1 | 5.10 |
| CL | Williams, D.Williams, Devin † >> | 28 | 2023 | R | 73 | 79 | 0 | 5 | 4 | 1.77 | .262 | 1.07 | 5.1 | 4.5 | 8.5 | 86.1 | 49 | 17 | 17 | 2 | 43 | 81 | 0 | 49 | 1 | 0 | 0 | 0 | 0 | 2.92 |