| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 35 | 35 | 15 | 16 | 4.16 | .312 | 1.34 | 9.4 | 2.7 | 5.6 | 235.2 | 245 | 114 | 109 | 23 | 70 | 145 | 4 | 0 | 0 | 2 | 18 | 5 | 3 | 4.00 |
| SP | Brown, M.Brown, Mordecai † >> | 32 | 1908 | R | 85 | 33 | 33 | 14 | 11 | 3.24 | .276 | 1.11 | 7.6 | 2.4 | 4.7 | 236.1 | 199 | 89 | 85 | 15 | 64 | 123 | 8 | 0 | 0 | 3 | 21 | 7 | 3 | 3.69 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 32 | 32 | 15 | 7 | 4.65 | .337 | 1.49 | 10.1 | 3.3 | 8.2 | 191.2 | 215 | 105 | 99 | 24 | 71 | 174 | 2 | 0 | 0 | 0 | 17 | 6 | 5 | 4.02 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 32 | 31 | 11 | 10 | 5.45 | .313 | 1.36 | 9.6 | 2.7 | 5.1 | 183.1 | 196 | 119 | 111 | 28 | 54 | 103 | 1 | 0 | 0 | 0 | 10 | 1 | 4 | 4.77 |
| CL | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 85 | 73 | 0 | 8 | 6 | 3.29 | .265 | 1.06 | 8.2 | 1.4 | 8.6 | 76.2 | 69 | 29 | 28 | 9 | 12 | 73 | 0 | 42 | 9 | 0 | 0 | 2 | 0 | 3.17 |
| SU | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 69 | 0 | 4 | 0 | 2.40 | .253 | 0.99 | 6.7 | 2.3 | 7.7 | 78.2 | 58 | 25 | 21 | 4 | 20 | 67 | 0 | 6 | 4 | 0 | 0 | 2 | 7 | 2.79 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 71 | 0 | 4 | 3 | 3.35 | .251 | 0.98 | 6.6 | 2.3 | 5.0 | 83.1 | 61 | 33 | 31 | 15 | 21 | 46 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 5.07 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 47 | 0 | 3 | 2 | 3.66 | .289 | 1.22 | 7.8 | 3.3 | 7.8 | 46.2 | 40 | 19 | 19 | 9 | 17 | 40 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.91 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 43 | 0 | 4 | 1 | 3.48 | .311 | 1.28 | 7.7 | 4.0 | 7.7 | 41.1 | 35 | 16 | 16 | 6 | 18 | 35 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 4.73 |