| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 25 | 25 | 8 | 11 | 3.67 | .269 | 1.10 | 7.9 | 2.0 | 8.5 | 189.0 | 165 | 79 | 77 | 25 | 42 | 179 | 5 | 0 | 0 | 1 | 14 | 2 | 3 | 3.52 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 85 | 24 | 24 | 8 | 11 | 5.05 | .321 | 1.39 | 9.2 | 3.4 | 7.8 | 142.2 | 145 | 82 | 80 | 22 | 53 | 123 | 0 | 0 | 0 | 0 | 12 | 4 | 5 | 4.49 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 73 | 24 | 24 | 7 | 8 | 5.07 | .314 | 1.34 | 8.6 | 3.5 | 5.7 | 147.1 | 140 | 84 | 83 | 16 | 57 | 93 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 4.41 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 23 | 23 | 7 | 11 | 5.43 | .330 | 1.47 | 7.8 | 5.4 | 8.0 | 141.0 | 122 | 88 | 85 | 19 | 85 | 126 | 0 | 0 | 0 | 0 | 10 | 1 | 3 | 4.79 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 67 | 0 | 2 | 3 | 3.88 | .296 | 1.21 | 8.7 | 2.3 | 9.0 | 92.2 | 89 | 42 | 40 | 10 | 23 | 92 | 0 | 3 | 5 | 0 | 0 | 5 | 2 | 3.33 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 65 | 0 | 5 | 4 | 2.57 | .274 | 1.10 | 8.6 | 1.3 | 8.3 | 84.0 | 80 | 29 | 24 | 4 | 12 | 77 | 0 | 7 | 3 | 0 | 0 | 3 | 0 | 2.32 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 50 | 0 | 2 | 3 | 2.75 | .283 | 1.17 | 5.9 | 4.6 | 9.0 | 59.0 | 39 | 19 | 18 | 7 | 30 | 59 | 0 | 9 | 3 | 0 | 0 | 1 | 1 | 4.12 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 36 | 0 | 3 | 5 | 5.45 | .357 | 1.61 | 8.8 | 6.0 | 10.2 | 39.2 | 38 | 24 | 24 | 4 | 26 | 44 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.23 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 34 | 0 | 3 | 1 | 5.40 | .317 | 1.39 | 8.3 | 4.4 | 10.3 | 41.2 | 38 | 25 | 25 | 7 | 20 | 47 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.39 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 14 | 0 | 1 | 3 | 3.65 | .362 | 1.70 | 11.3 | 4.5 | 7.9 | 24.2 | 30 | 10 | 10 | 1 | 12 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.29 |