| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 40 | 40 | 18 | 13 | 3.83 | .253 | 1.00 | 7.0 | 2.0 | 10.7 | 293.2 | 228 | 132 | 125 | 45 | 66 | 347 | 15 | 0 | 0 | 4 | 23 | 4 | 4 | 3.34 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 88 | 38 | 38 | 16 | 14 | 4.47 | .291 | 1.21 | 8.1 | 2.8 | 6.6 | 237.2 | 212 | 122 | 118 | 48 | 75 | 173 | 1 | 0 | 0 | 1 | 18 | 6 | 5 | 5.20 |
| SP | Martinez, R.Martinez, Ramon >> | 22 | 1990 | R | 79 | 36 | 36 | 16 | 11 | 5.76 | .330 | 1.44 | 9.5 | 3.5 | 6.0 | 215.2 | 226 | 147 | 138 | 45 | 84 | 144 | 5 | 0 | 0 | 1 | 15 | 9 | 6 | 5.68 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 81 | 74 | 0 | 4 | 1 | 3.72 | .293 | 1.23 | 7.7 | 3.5 | 9.7 | 67.2 | 57 | 28 | 28 | 12 | 26 | 72 | 0 | 11 | 3 | 0 | 0 | 1 | 2 | 4.39 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 87 | 101 | 0 | 0 | 1 | 4.55 | .299 | 1.28 | 7.6 | 4.0 | 9.6 | 63.1 | 53 | 34 | 32 | 10 | 28 | 67 | 0 | 4 | 3 | 0 | 0 | 0 | 2 | 4.27 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 26 | 2006 | R | 94 | 96 | 0 | 4 | 9 | 4.85 | .309 | 1.32 | 8.5 | 3.4 | 9.2 | 98.1 | 93 | 55 | 53 | 23 | 37 | 100 | 0 | 12 | 9 | 0 | 0 | 2 | 1 | 5.20 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 73 | 29 | 0 | 2 | 0 | 2.38 | .209 | 0.76 | 4.5 | 2.4 | 8.7 | 34.0 | 17 | 9 | 9 | 2 | 9 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.71 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 76 | 19 | 0 | 3 | 0 | 2.37 | .296 | 1.26 | 9.0 | 2.4 | 9.0 | 19.0 | 19 | 5 | 5 | 2 | 5 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.16 |