| SP | Verlander, J.Verlander, Justin # >> | 29 | 2012 | R | 86 | 33 | 33 | 12 | 10 | 4.57 | .309 | 1.31 | 8.9 | 3.0 | 9.4 | 204.2 | 201 | 105 | 104 | 29 | 67 | 212 | 1 | 0 | 0 | 0 | 18 | 6 | 1 | 3.84 |
| SP | Morris, J.Morris, Jack # >> | 29 | 1984 | R | 24 | 33 | 33 | 8 | 20 | 5.18 | .329 | 1.44 | 9.7 | 3.3 | 6.3 | 187.2 | 202 | 115 | 108 | 34 | 69 | 131 | 2 | 0 | 0 | 0 | 15 | 5 | 9 | 5.15 |
| SP | Scherzer, M.Scherzer, Max # >> | 28 | 2012 | R | 29 | 33 | 33 | 7 | 14 | 5.34 | .320 | 1.40 | 9.2 | 3.3 | 9.3 | 167.0 | 171 | 102 | 99 | 27 | 62 | 172 | 0 | 0 | 0 | 0 | 14 | 3 | 3 | 4.21 |
| SP | Rogers, K.Rogers, Kenny # >> | 42 | 2006 | L | 25 | 31 | 31 | 6 | 10 | 5.63 | .355 | 1.63 | 10.5 | 4.1 | 6.7 | 155.0 | 181 | 102 | 97 | 30 | 71 | 116 | 0 | 0 | 0 | 0 | 9 | 4 | 3 | 5.47 |
| RP | Henneman, M.Henneman, Mike >> | 26 | 1987 | R | 31 | 85 | 0 | 6 | 4 | 4.84 | .361 | 1.67 | 11.0 | 4.1 | 6.3 | 111.2 | 136 | 62 | 60 | 20 | 50 | 78 | 0 | 2 | 4 | 0 | 0 | 3 | 2 | 5.37 |
| RP | Valverde, J.Valverde, Jose >> | 33 | 2012 | R | 26 | 50 | 0 | 4 | 0 | 3.40 | .329 | 1.47 | 9.0 | 4.3 | 6.1 | 50.1 | 50 | 23 | 19 | 7 | 24 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.90 |
| RP | Lopez, A.Lopez, Aurelio >> | 36 | 1984 | R | 35 | 44 | 0 | 3 | 1 | 2.48 | .260 | 1.06 | 5.7 | 3.9 | 4.8 | 65.1 | 41 | 18 | 18 | 5 | 28 | 35 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.22 |
| CL | Hernandez, W.Hernandez, Willie † >> | 30 | 1984 | L | 80 | 72 | 0 | 7 | 12 | 4.54 | .322 | 1.41 | 9.6 | 3.2 | 6.2 | 81.1 | 86 | 44 | 41 | 14 | 29 | 56 | 0 | 41 | 7 | 0 | 0 | 1 | 1 | 4.98 |
| SP | Bonderman, J.Bonderman, Jeremy >> | 24 | 2006 | R | 19 | 35 | 0 | 5 | 4 | 5.96 | .363 | 1.68 | 10.6 | 4.6 | 6.4 | 128.1 | 151 | 87 | 85 | 22 | 65 | 91 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.41 |
| SU | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 54 | 63 | 0 | 0 | 4 | 5.16 | .353 | 1.63 | 8.2 | 6.6 | 8.5 | 59.1 | 54 | 35 | 34 | 12 | 43 | 56 | 0 | 5 | 8 | 0 | 0 | 0 | 2 | 5.93 |