| SP | Verlander, J.Verlander, Justin $$ >> | 36 | 2019 | R | 100 | 36 | 36 | 13 | 13 | 3.90 | .266 | 1.07 | 6.8 | 2.8 | 9.7 | 235.2 | 178 | 104 | 102 | 38 | 74 | 254 | 5 | 0 | 0 | 4 | 20 | 4 | 1 | 3.94 |
| SP | Martinez, P.Martinez, Pedro $$ >> | 29 | 2000 | R | 100 | 34 | 34 | 17 | 12 | 3.39 | .257 | 1.01 | 6.9 | 2.2 | 8.6 | 244.1 | 187 | 97 | 92 | 28 | 60 | 232 | 10 | 0 | 0 | 4 | 18 | 6 | 1 | 3.40 |
| SP | McClanahan, S.McClanahan, Shane # >> | 25 | 2022 | L | 92 | 34 | 34 | 15 | 6 | 4.30 | .298 | 1.22 | 8.7 | 2.3 | 7.6 | 190.2 | 184 | 92 | 91 | 32 | 49 | 160 | 0 | 0 | 0 | 0 | 17 | 10 | 4 | 4.44 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 91 | 33 | 33 | 13 | 16 | 3.80 | .289 | 1.21 | 7.9 | 3.0 | 8.3 | 215.1 | 189 | 96 | 91 | 34 | 71 | 198 | 8 | 0 | 0 | 1 | 18 | 3 | 1 | 4.25 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 73 | 33 | 32 | 15 | 6 | 2.86 | .292 | 1.22 | 6.5 | 4.5 | 4.6 | 214.1 | 155 | 76 | 68 | 11 | 106 | 110 | 3 | 1 | 0 | 1 | 25 | 4 | 3 | 4.18 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 94 | 102 | 0 | 6 | 5 | 2.89 | .247 | 0.97 | 6.5 | 2.2 | 8.8 | 109.0 | 79 | 37 | 35 | 10 | 27 | 106 | 0 | 10 | 5 | 0 | 0 | 1 | 0 | 3.02 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 93 | 75 | 0 | 6 | 0 | 3.33 | .277 | 1.12 | 7.8 | 2.3 | 8.9 | 78.1 | 68 | 29 | 29 | 5 | 20 | 77 | 0 | 8 | 0 | 0 | 0 | 2 | 3 | 2.71 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 88 | 92 | 0 | 6 | 5 | 3.21 | .288 | 1.17 | 6.9 | 3.6 | 7.3 | 84.0 | 64 | 30 | 30 | 5 | 34 | 68 | 0 | 8 | 4 | 0 | 0 | 4 | 8 | 3.51 |
| RP | Brewer, J.Brewer, Jim # >> | 35 | 1972 | L | 86 | 61 | 0 | 2 | 3 | 5.13 | .307 | 1.31 | 8.2 | 3.6 | 4.8 | 47.1 | 43 | 27 | 27 | 9 | 19 | 25 | 0 | 10 | 1 | 0 | 0 | 1 | 1 | 5.70 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 82 | 26 | 0 | 3 | 1 | 4.01 | .327 | 1.46 | 8.6 | 4.9 | 7.5 | 24.2 | 23 | 11 | 11 | 3 | 13 | 20 | 0 | 1 | 3 | 0 | 0 | 0 | 3 | 4.58 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 83 | 27 | 0 | 3 | 1 | 2.91 | .282 | 1.18 | 7.1 | 3.4 | 8.2 | 34.0 | 27 | 11 | 11 | 2 | 13 | 31 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.09 |