| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 99 | 12 | 12 | 4 | 3 | 5.06 | .358 | 1.63 | 11.1 | 3.8 | 9.0 | 74.2 | 91 | 42 | 42 | 12 | 31 | 74 | 1 | 0 | 0 | 0 | 6 | 3 | 1 | 4.49 |
| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 80 | 12 | 12 | 5 | 4 | 5.70 | .335 | 1.43 | 9.5 | 3.5 | 9.5 | 72.2 | 76 | 47 | 46 | 19 | 28 | 76 | 0 | 0 | 0 | 0 | 7 | 6 | 1 | 5.74 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 78 | 12 | 12 | 5 | 3 | 5.24 | .327 | 1.43 | 9.9 | 3.0 | 6.1 | 68.2 | 75 | 40 | 40 | 8 | 23 | 46 | 1 | 0 | 0 | 1 | 5 | 2 | 1 | 4.28 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 12 | 12 | 3 | 5 | 4.99 | .334 | 1.51 | 10.3 | 3.3 | 5.5 | 83.0 | 95 | 46 | 46 | 15 | 30 | 51 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 5.20 |
| SP | Loaiza, E.Loaiza, Esteban # >> | 32 | 2003 | R | 58 | 12 | 12 | 3 | 5 | 7.12 | .376 | 1.76 | 11.4 | 4.4 | 6.7 | 67.0 | 85 | 54 | 53 | 13 | 33 | 50 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 5.64 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 34 | 0 | 2 | 6 | 3.66 | .286 | 1.18 | 8.3 | 2.5 | 8.8 | 51.2 | 47 | 23 | 21 | 6 | 14 | 50 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.45 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 68 | 20 | 0 | 2 | 1 | 3.38 | .314 | 1.38 | 8.3 | 4.1 | 7.9 | 24.0 | 22 | 9 | 9 | 3 | 11 | 21 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.25 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 57 | 17 | 0 | 0 | 1 | 2.81 | .273 | 1.13 | 7.9 | 2.3 | 11.8 | 16.0 | 14 | 6 | 5 | 3 | 4 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 45 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 49 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Burnett, A.Burnett, A.J. >> | 25 | 2002 | R | 56 | 7 | 0 | 0 | 1 | 6.10 | .436 | 2.23 | 12.6 | 8.1 | 9.0 | 10.1 | 14 | 7 | 7 | 2 | 9 | 10 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 6.60 |