| SP | Perez, O.Perez, Odalis # >> | 25 | 2002 | L | 81 | 26 | 26 | 14 | 6 | 3.13 | .285 | 1.15 | 8.1 | 2.3 | 7.0 | 175.1 | 158 | 65 | 61 | 15 | 44 | 137 | 4 | 0 | 0 | 2 | 19 | 8 | 1 | 3.44 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 76 | 25 | 23 | 11 | 7 | 4.66 | .330 | 1.44 | 8.8 | 4.1 | 9.6 | 139.0 | 136 | 72 | 72 | 12 | 64 | 149 | 2 | 0 | 0 | 1 | 14 | 5 | 2 | 3.47 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 25 | 25 | 8 | 9 | 4.30 | .328 | 1.43 | 9.2 | 3.7 | 8.3 | 157.0 | 161 | 81 | 75 | 18 | 64 | 144 | 2 | 0 | 0 | 0 | 14 | 5 | 15 | 3.97 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 60 | 68 | 0 | 2 | 1 | 4.37 | .318 | 1.37 | 7.9 | 4.6 | 11.5 | 55.2 | 48 | 27 | 27 | 4 | 28 | 70 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 3.04 |
| SU | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 63 | 53 | 0 | 2 | 4 | 4.19 | .285 | 1.18 | 8.1 | 2.6 | 6.8 | 68.2 | 61 | 33 | 32 | 6 | 20 | 51 | 0 | 3 | 7 | 0 | 0 | 1 | 0 | 3.57 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 35 | 0 | 4 | 3 | 7.39 | .340 | 1.52 | 8.4 | 5.5 | 8.7 | 31.2 | 29 | 26 | 26 | 7 | 19 | 30 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 5.94 |
| CL | Papelbon, J.Papelbon, Jonathan † >> | 26 | 2006 | R | 93 | 49 | 0 | 2 | 6 | 3.83 | .256 | 1.03 | 6.4 | 2.9 | 8.1 | 49.1 | 35 | 21 | 21 | 3 | 16 | 44 | 0 | 29 | 3 | 0 | 0 | 0 | 0 | 2.98 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 15 | 10 | 2 | 4 | 5.33 | .327 | 1.43 | 10.2 | 2.8 | 6.7 | 77.2 | 87 | 46 | 46 | 13 | 24 | 57 | 2 | 0 | 0 | 0 | 4 | 2 | 1 | 4.73 |