| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 87 | 32 | 32 | 14 | 11 | 3.94 | .288 | 1.17 | 8.3 | 2.2 | 6.8 | 205.2 | 190 | 92 | 90 | 32 | 51 | 156 | 5 | 0 | 0 | 1 | 17 | 8 | 4 | 4.37 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 32 | 32 | 9 | 15 | 7.18 | .361 | 1.66 | 11.4 | 3.5 | 7.4 | 150.1 | 190 | 128 | 120 | 38 | 59 | 124 | 0 | 0 | 0 | 0 | 9 | 6 | 3 | 5.94 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 31 | 31 | 8 | 11 | 6.93 | .373 | 1.76 | 10.9 | 5.0 | 7.3 | 150.2 | 181 | 122 | 116 | 33 | 84 | 122 | 1 | 0 | 0 | 0 | 9 | 4 | 4 | 5.99 |
| CL | Soriano, R.Soriano, Rafael † >> | 24 | 2003 | R | 97 | 52 | 0 | 3 | 5 | 4.53 | .302 | 1.25 | 8.2 | 3.2 | 8.8 | 57.2 | 52 | 30 | 29 | 6 | 20 | 56 | 0 | 28 | 3 | 0 | 0 | 3 | 0 | 3.61 |
| SU | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 68 | 0 | 3 | 3 | 2.74 | .321 | 1.41 | 6.8 | 5.9 | 10.0 | 69.0 | 52 | 23 | 21 | 5 | 45 | 77 | 0 | 2 | 3 | 0 | 0 | 1 | 4 | 3.71 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 73 | 74 | 0 | 1 | 4 | 3.09 | .284 | 1.17 | 7.2 | 3.3 | 7.1 | 87.1 | 70 | 33 | 30 | 6 | 32 | 69 | 0 | 2 | 7 | 0 | 0 | 2 | 0 | 3.48 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 72 | 54 | 0 | 8 | 1 | 5.12 | .320 | 1.40 | 8.8 | 3.7 | 10.7 | 58.0 | 57 | 34 | 33 | 7 | 24 | 69 | 0 | 3 | 3 | 0 | 0 | 1 | 5 | 3.48 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 70 | 38 | 0 | 0 | 0 | 1.91 | .250 | 0.96 | 5.7 | 2.9 | 10.0 | 47.0 | 30 | 11 | 10 | 2 | 15 | 52 | 0 | 2 | 1 | 0 | 0 | 2 | 2 | 2.43 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 40 | 30 | 0 | 0 | 2 | 4.58 | .298 | 1.22 | 6.7 | 4.4 | 6.9 | 35.1 | 26 | 18 | 18 | 5 | 17 | 27 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.94 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 53 | 34 | 0 | 4 | 3 | 5.40 | .328 | 1.41 | 9.7 | 3.0 | 7.4 | 136.2 | 147 | 84 | 82 | 31 | 46 | 112 | 0 | 0 | 0 | 0 | 0 | 7 | 4 | 5.49 |