| SP | Santana, J.Santana, Johan † >> | 25 | 2004 | L | 100 | 26 | 26 | 10 | 10 | 3.83 | .303 | 1.27 | 8.7 | 2.7 | 8.7 | 181.0 | 175 | 78 | 77 | 19 | 54 | 174 | 4 | 0 | 0 | 1 | 19 | 7 | 7 | 3.45 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 70 | 25 | 25 | 4 | 14 | 5.50 | .320 | 1.39 | 9.7 | 2.8 | 5.8 | 147.1 | 159 | 96 | 90 | 32 | 46 | 95 | 0 | 0 | 0 | 0 | 8 | 3 | 6 | 5.54 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 49 | 24 | 24 | 6 | 13 | 6.40 | .358 | 1.65 | 11.9 | 2.9 | 7.2 | 135.0 | 179 | 100 | 96 | 23 | 44 | 108 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 4.66 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 24 | 24 | 7 | 9 | 5.18 | .324 | 1.41 | 7.3 | 5.5 | 8.8 | 140.2 | 113 | 81 | 81 | 16 | 85 | 137 | 0 | 0 | 0 | 0 | 6 | 4 | 4 | 4.44 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 67 | 0 | 6 | 6 | 3.16 | .288 | 1.18 | 7.3 | 3.3 | 9.9 | 105.1 | 85 | 37 | 37 | 11 | 39 | 115 | 0 | 7 | 8 | 0 | 0 | 4 | 0 | 3.40 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 69 | 0 | 4 | 1 | 3.89 | .296 | 1.22 | 8.5 | 2.6 | 6.2 | 83.1 | 78 | 36 | 36 | 14 | 24 | 57 | 0 | 12 | 2 | 0 | 0 | 3 | 4 | 4.80 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 47 | 47 | 0 | 1 | 5 | 4.38 | .325 | 1.42 | 9.5 | 3.4 | 6.0 | 51.1 | 54 | 27 | 25 | 6 | 19 | 34 | 0 | 2 | 3 | 0 | 0 | 1 | 3 | 4.37 |
| RP | Aardsma, D.Aardsma, David >> | 28 | 2009 | R | 38 | 41 | 0 | 3 | 0 | 4.80 | .357 | 1.60 | 7.6 | 6.8 | 9.8 | 45.0 | 38 | 25 | 24 | 9 | 34 | 49 | 0 | 4 | 0 | 0 | 0 | 3 | 0 | 5.89 |
| SP | Mulder, M.Mulder, Mark >> | 24 | 2001 | L | 30 | 26 | 0 | 2 | 5 | 5.49 | .342 | 1.51 | 10.1 | 3.5 | 8.1 | 41.0 | 46 | 25 | 25 | 5 | 16 | 37 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 4.10 |