| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 32 | 32 | 15 | 10 | 3.70 | .293 | 1.22 | 8.4 | 2.6 | 9.4 | 206.2 | 193 | 89 | 85 | 32 | 59 | 216 | 0 | 0 | 0 | 0 | 20 | 5 | 0 | 3.85 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 32 | 32 | 10 | 16 | 4.87 | .308 | 1.31 | 8.3 | 3.4 | 9.0 | 205.1 | 190 | 116 | 111 | 27 | 78 | 204 | 6 | 0 | 0 | 1 | 15 | 6 | 2 | 3.95 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 31 | 31 | 10 | 13 | 4.10 | .321 | 1.39 | 9.2 | 3.4 | 6.4 | 217.1 | 221 | 104 | 99 | 27 | 82 | 154 | 4 | 0 | 0 | 1 | 18 | 5 | 4 | 4.40 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 30 | 30 | 6 | 11 | 6.11 | .347 | 1.58 | 10.8 | 3.6 | 4.7 | 185.2 | 221 | 133 | 126 | 35 | 73 | 96 | 6 | 0 | 0 | 0 | 8 | 2 | 1 | 5.64 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 83 | 0 | 5 | 1 | 3.38 | .276 | 1.13 | 7.9 | 2.3 | 9.2 | 104.0 | 91 | 39 | 39 | 15 | 27 | 106 | 0 | 13 | 1 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 64 | 0 | 3 | 6 | 4.44 | .295 | 1.23 | 7.2 | 3.9 | 9.2 | 79.0 | 63 | 39 | 39 | 8 | 34 | 81 | 0 | 7 | 2 | 0 | 0 | 2 | 2 | 3.63 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 46 | 0 | 5 | 2 | 4.56 | .347 | 1.52 | 8.7 | 5.1 | 7.3 | 53.1 | 51 | 28 | 27 | 5 | 30 | 43 | 0 | 5 | 1 | 0 | 0 | 4 | 4 | 4.53 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 41 | 0 | 6 | 0 | 3.05 | .250 | 0.98 | 7.0 | 1.9 | 7.7 | 62.0 | 48 | 24 | 21 | 9 | 13 | 53 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.85 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 2 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 0.0 | 2.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 14 | 0 | 2 | 2 | 6.75 | .323 | 1.43 | 10.9 | 2.2 | 4.7 | 29.1 | 35 | 22 | 22 | 9 | 7 | 15 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 6.72 |