| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 29 | 29 | 13 | 13 | 3.81 | .286 | 1.19 | 8.1 | 2.7 | 4.6 | 210.1 | 188 | 94 | 89 | 23 | 62 | 107 | 9 | 0 | 0 | 3 | 14 | 3 | 5 | 4.33 |
| SP | Ryan, N.Ryan, Nolan † $$ >> | 44 | 1991 | R | 73 | 28 | 28 | 14 | 4 | 3.49 | .297 | 1.22 | 6.2 | 4.8 | 7.0 | 190.2 | 130 | 77 | 74 | 15 | 102 | 147 | 0 | 0 | 0 | 0 | 17 | 10 | 8 | 4.25 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 27 | 27 | 13 | 10 | 2.93 | .273 | 1.12 | 7.7 | 2.4 | 7.7 | 199.1 | 170 | 68 | 65 | 20 | 53 | 170 | 2 | 0 | 0 | 0 | 21 | 2 | 3 | 3.43 |
| SP | Reulbach, E.Reulbach, Ed † >> | 24 | 1906 | R | 61 | 27 | 27 | 15 | 8 | 3.09 | .278 | 1.16 | 6.5 | 4.0 | 4.1 | 180.2 | 129 | 67 | 62 | 13 | 80 | 81 | 2 | 0 | 0 | 1 | 21 | 0 | 3 | 4.37 |
| SP | Fernandez, S.Fernandez, Sid $ >> | 23 | 1985 | L | 49 | 25 | 25 | 14 | 5 | 3.56 | .297 | 1.26 | 6.7 | 4.7 | 7.8 | 161.2 | 120 | 66 | 64 | 18 | 84 | 140 | 1 | 0 | 0 | 1 | 17 | 1 | 3 | 4.30 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 44 | 55 | 0 | 3 | 2 | 2.06 | .234 | 0.91 | 4.6 | 3.6 | 8.0 | 35.0 | 18 | 9 | 8 | 2 | 14 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.17 |
| RP | Sambito, J.Sambito, Joe >> | 28 | 1980 | L | 33 | 82 | 0 | 0 | 0 | 2.63 | .301 | 1.29 | 7.9 | 3.7 | 5.5 | 41.0 | 36 | 14 | 12 | 4 | 17 | 25 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 4.29 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 37 | 0 | 6 | 4 | 3.00 | .276 | 1.12 | 6.2 | 3.9 | 5.4 | 42.0 | 29 | 15 | 14 | 2 | 18 | 25 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 3.79 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 9 | 0 | 2 | 1 | 1.71 | .222 | 0.81 | 4.7 | 2.6 | 7.3 | 21.0 | 11 | 4 | 4 | 2 | 6 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.62 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 58 | 0 | 1 | 3 | 2.22 | .237 | 0.93 | 5.9 | 2.6 | 6.9 | 52.2 | 34 | 16 | 13 | 2 | 15 | 40 | 0 | 49 | 2 | 0 | 0 | 0 | 2 | 2.83 |