| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 33 | 33 | 12 | 16 | 4.02 | .299 | 1.25 | 9.0 | 2.3 | 9.0 | 255.1 | 256 | 126 | 114 | 38 | 64 | 256 | 11 | 0 | 0 | 2 | 17 | 6 | 4 | 3.75 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 32 | 32 | 13 | 11 | 5.06 | .342 | 1.52 | 10.1 | 3.7 | 5.0 | 170.2 | 191 | 98 | 96 | 18 | 69 | 95 | 0 | 0 | 0 | 0 | 9 | 6 | 1 | 4.58 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 31 | 31 | 12 | 17 | 5.10 | .304 | 1.27 | 8.3 | 3.2 | 5.0 | 219.0 | 202 | 127 | 124 | 23 | 77 | 121 | 7 | 0 | 0 | 5 | 13 | 8 | 1 | 4.42 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 31 | 7 | 14 | 6.12 | .351 | 1.59 | 10.8 | 3.5 | 4.1 | 213.1 | 256 | 154 | 145 | 28 | 84 | 96 | 3 | 0 | 0 | 1 | 7 | 6 | 5 | 5.08 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 30 | 9 | 15 | 6.15 | .366 | 1.71 | 11.1 | 4.3 | 5.7 | 190.1 | 235 | 140 | 130 | 29 | 90 | 121 | 1 | 0 | 0 | 0 | 11 | 4 | 5 | 5.19 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 84 | 0 | 6 | 5 | 3.16 | .269 | 1.08 | 6.8 | 2.9 | 9.0 | 114.0 | 86 | 42 | 40 | 13 | 37 | 114 | 0 | 6 | 5 | 0 | 0 | 3 | 2 | 3.54 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 71 | 0 | 3 | 3 | 5.42 | .298 | 1.24 | 7.9 | 3.3 | 5.6 | 88.0 | 77 | 53 | 53 | 15 | 32 | 55 | 0 | 9 | 2 | 0 | 0 | 3 | 0 | 5.16 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 61 | 0 | 1 | 6 | 4.71 | .329 | 1.46 | 9.1 | 4.1 | 7.7 | 70.2 | 71 | 38 | 37 | 7 | 32 | 60 | 0 | 9 | 4 | 0 | 0 | 1 | 3 | 4.00 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 35 | 0 | 1 | 2 | 2.86 | .311 | 1.33 | 8.2 | 4.0 | 4.8 | 34.2 | 31 | 11 | 11 | 0 | 15 | 18 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.35 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 35 | 0 | 2 | 1 | 4.46 | .298 | 1.28 | 8.1 | 3.4 | 9.0 | 42.1 | 38 | 22 | 21 | 7 | 16 | 42 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 4.31 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 6 | 0 | 0 | 1 | 6.14 | .436 | 2.32 | 14.1 | 7.7 | 7.7 | 7.1 | 11 | 7 | 5 | 2 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.57 |