| SP | McNally, D.McNally, Dave $ >> | 26 | 1968 | L | 97 | 32 | 32 | 11 | 12 | 3.91 | .289 | 1.19 | 8.1 | 2.6 | 6.1 | 223.1 | 201 | 110 | 97 | 29 | 64 | 151 | 5 | 0 | 0 | 1 | 17 | 7 | 3 | 4.29 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 89 | 26 | 26 | 11 | 12 | 3.22 | .271 | 1.11 | 7.5 | 2.5 | 4.2 | 187.1 | 156 | 71 | 67 | 13 | 52 | 87 | 5 | 0 | 0 | 0 | 16 | 1 | 5 | 3.82 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 90 | 33 | 33 | 10 | 16 | 5.24 | .324 | 1.42 | 10.6 | 2.2 | 8.5 | 197.2 | 231 | 125 | 115 | 28 | 49 | 186 | 1 | 0 | 0 | 0 | 17 | 4 | 2 | 3.77 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 94 | 86 | 0 | 5 | 5 | 4.40 | .321 | 1.39 | 8.4 | 4.2 | 9.8 | 77.2 | 72 | 44 | 38 | 9 | 36 | 84 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 3.82 |
| RP | Munoz, A.Munoz, Andres >> | 23 | 2022 | R | 75 | 63 | 0 | 1 | 1 | 2.56 | .272 | 1.11 | 7.2 | 2.9 | 10.2 | 59.2 | 47 | 19 | 17 | 3 | 19 | 67 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 2.41 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 86 | 61 | 0 | 3 | 6 | 3.47 | .281 | 1.17 | 6.7 | 4.0 | 10.4 | 59.2 | 44 | 26 | 23 | 8 | 26 | 68 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 3.78 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 99 | 81 | 0 | 1 | 7 | 4.23 | .287 | 1.18 | 6.9 | 3.7 | 9.1 | 89.1 | 68 | 44 | 42 | 15 | 37 | 90 | 0 | 8 | 3 | 0 | 0 | 3 | 0 | 4.52 |