| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 75 | 25 | 25 | 9 | 10 | 4.95 | .308 | 1.32 | 8.9 | 3.0 | 7.7 | 149.0 | 148 | 82 | 82 | 24 | 49 | 127 | 0 | 0 | 0 | 0 | 14 | 2 | 3 | 4.42 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 76 | 24 | 24 | 4 | 15 | 5.21 | .331 | 1.46 | 9.5 | 3.7 | 7.3 | 133.0 | 140 | 81 | 77 | 19 | 54 | 108 | 1 | 0 | 0 | 0 | 10 | 3 | 1 | 4.52 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 78 | 23 | 23 | 4 | 12 | 4.61 | .288 | 1.19 | 7.2 | 3.6 | 8.1 | 142.2 | 113 | 73 | 73 | 21 | 57 | 128 | 0 | 0 | 0 | 0 | 12 | 3 | 5 | 4.39 |
| SP | Paddack, C.Paddack, Chris # >> | 23 | 2019 | R | 73 | 23 | 23 | 6 | 10 | 4.50 | .297 | 1.25 | 8.4 | 2.8 | 7.6 | 126.0 | 118 | 66 | 63 | 21 | 39 | 107 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 4.47 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 93 | 82 | 0 | 0 | 0 | 2.44 | .238 | 0.92 | 5.4 | 3.0 | 9.4 | 73.2 | 44 | 20 | 20 | 5 | 24 | 76 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 2.84 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 75 | 80 | 0 | 1 | 2 | 5.30 | .324 | 1.42 | 9.3 | 3.5 | 8.0 | 54.1 | 56 | 32 | 32 | 6 | 21 | 48 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.89 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 83 | 71 | 0 | 3 | 0 | 3.20 | .290 | 1.19 | 7.9 | 2.9 | 8.7 | 56.1 | 49 | 20 | 20 | 5 | 18 | 54 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 3.30 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 72 | 67 | 0 | 1 | 1 | 2.28 | .241 | 0.95 | 4.8 | 3.8 | 10.0 | 47.1 | 25 | 12 | 12 | 5 | 20 | 52 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.45 |
| RP | Mujica, E.Mujica, Edward >> | 26 | 2010 | R | 52 | 63 | 0 | 5 | 2 | 2.32 | .230 | 0.88 | 6.4 | 1.5 | 7.9 | 66.0 | 47 | 18 | 17 | 7 | 11 | 58 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 3.17 |
| SP | Luebke, C.Luebke, Cory >> | 26 | 2011 | L | 61 | 18 | 0 | 2 | 4 | 7.45 | .356 | 1.60 | 9.9 | 4.7 | 6.2 | 19.1 | 21 | 17 | 16 | 3 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.42 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 50 | 0 | 3 | 3 | 2.51 | .265 | 1.08 | 6.2 | 3.6 | 8.5 | 57.1 | 39 | 17 | 16 | 4 | 23 | 54 | 0 | 18 | 3 | 0 | 0 | 0 | 0 | 3.23 |