| SP | Sale, C.Sale, Chris # $ >> | 29 | 2018 | L | 99 | 35 | 35 | 8 | 14 | 4.60 | .322 | 1.39 | 9.0 | 3.6 | 9.4 | 166.1 | 166 | 92 | 85 | 17 | 66 | 174 | 0 | 0 | 0 | 0 | 8 | 5 | 2 | 3.52 |
| SP | Scherzer, M.Scherzer, Max >> | 34 | 2018 | R | 95 | 32 | 32 | 11 | 10 | 3.77 | .281 | 1.13 | 7.6 | 2.5 | 9.5 | 184.0 | 155 | 77 | 77 | 29 | 52 | 195 | 0 | 0 | 0 | 0 | 18 | 9 | 1 | 3.92 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 73 | 95 | 0 | 2 | 2 | 3.42 | .281 | 1.15 | 5.5 | 4.8 | 9.3 | 121.0 | 74 | 47 | 46 | 16 | 65 | 125 | 0 | 5 | 3 | 0 | 0 | 3 | 8 | 4.34 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 75 | 76 | 0 | 1 | 2 | 4.70 | .315 | 1.35 | 8.4 | 3.8 | 8.9 | 95.2 | 89 | 50 | 50 | 16 | 40 | 94 | 0 | 11 | 2 | 0 | 0 | 3 | 1 | 4.57 |
| RP | Marmol, C.Marmol, Carlos † >> | 28 | 2010 | R | 78 | 71 | 0 | 9 | 6 | 2.94 | .274 | 1.11 | 5.0 | 4.9 | 11.6 | 104.0 | 58 | 36 | 34 | 7 | 57 | 134 | 0 | 12 | 4 | 0 | 0 | 3 | 0 | 3.03 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 64 | 42 | 0 | 4 | 4 | 2.84 | .300 | 1.18 | 8.6 | 2.2 | 10.3 | 50.2 | 48 | 16 | 16 | 6 | 12 | 57 | 0 | 3 | 0 | 0 | 0 | 5 | 0 | 3.30 |
| RP | Hader, J.Hader, Josh # >> | 25 | 2019 | L | 84 | 112 | 0 | 3 | 4 | 4.09 | .261 | 1.00 | 6.2 | 2.8 | 10.5 | 114.1 | 79 | 52 | 52 | 19 | 35 | 133 | 0 | 3 | 2 | 0 | 0 | 7 | 0 | 3.94 |
| RP | Medlen, K.Medlen, Kris >> | 26 | 2012 | R | 68 | 45 | 0 | 4 | 8 | 5.06 | .300 | 1.21 | 8.9 | 2.1 | 6.9 | 69.1 | 68 | 39 | 39 | 16 | 16 | 53 | 0 | 3 | 2 | 0 | 0 | 5 | 0 | 5.39 |
| RP | Quisenberry, D.Quisenberry, Dan >> | 30 | 1983 | R | 40 | 39 | 0 | 0 | 1 | 5.68 | .321 | 1.36 | 10.3 | 2.2 | 6.5 | 50.2 | 57 | 32 | 32 | 10 | 12 | 36 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 5.06 |