| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 50 | 9 | 9 | 0 | 5 | 7.93 | .377 | 1.76 | 12.8 | 3.3 | 3.3 | 36.1 | 51 | 32 | 32 | 7 | 13 | 13 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 6.06 |
| SU | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 10 | 23 | 0 | 1 | 0 | 5.22 | .285 | 1.19 | 8.1 | 2.8 | 3.1 | 29.1 | 26 | 17 | 17 | 7 | 9 | 10 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 6.38 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 16 | 22 | 0 | 2 | 1 | 4.71 | .328 | 1.43 | 8.7 | 4.5 | 9.6 | 28.2 | 27 | 15 | 15 | 3 | 14 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.86 |
| RP | Thigpen, B.Thigpen, Bobby >> | 27 | 1990 | R | 4 | 16 | 0 | 0 | 2 | 4.26 | .305 | 1.32 | 9.0 | 2.8 | 5.7 | 19.0 | 19 | 9 | 9 | 5 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.11 |
| RP | Knebel, C.Knebel, Corey >> | 25 | 2017 | R | 24 | 18 | 0 | 0 | 0 | 2.21 | .307 | 1.28 | 6.3 | 5.4 | 10.4 | 20.1 | 14 | 5 | 5 | 1 | 12 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.30 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 26 | 0 | 2 | 3 | 3.38 | .316 | 1.35 | 8.7 | 3.8 | 5.9 | 26.2 | 25 | 13 | 10 | 1 | 11 | 17 | 0 | 13 | 4 | 0 | 0 | 1 | 0 | 3.58 |