| SP | Michels, B.Michels, Brad >> | 18 | 2021 | R | 100 | 11 | 11 | 9 | 0 | 1.54 | .179 | 0.61 | 4.6 | 0.9 | 8.6 | 93.1 | 48 | 16 | 16 | 4 | 9 | 89 | 7 | 0 | 0 | 4 | 10 | 4 | 0 | 2.06 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 11 | 11 | 5 | 3 | 4.15 | .258 | 1.03 | 8.5 | 0.9 | 5.9 | 73.2 | 69 | 35 | 34 | 8 | 7 | 48 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 3.44 |
| SP | Darvish, Y.Darvish, Yu >> | 33 | 2020 | R | 70 | 10 | 10 | 7 | 1 | 1.95 | .230 | 0.86 | 6.3 | 1.5 | 9.2 | 73.2 | 51 | 18 | 16 | 6 | 12 | 75 | 3 | 0 | 0 | 1 | 9 | 3 | 1 | 2.63 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 49 | 9 | 9 | 4 | 1 | 4.01 | .283 | 1.17 | 7.8 | 2.8 | 5.0 | 58.1 | 50 | 29 | 26 | 8 | 18 | 32 | 1 | 0 | 0 | 0 | 5 | 1 | 0 | 4.67 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 52 | 6 | 6 | 5 | 1 | 1.99 | .240 | 0.95 | 6.0 | 2.6 | 5.6 | 45.1 | 30 | 11 | 10 | 2 | 13 | 28 | 1 | 0 | 0 | 1 | 4 | 0 | 1 | 3.20 |
| SU | Robertson, D.Robertson, David >> | 32 | 2017 | R | 81 | 14 | 0 | 0 | 0 | 2.70 | .206 | 0.72 | 3.9 | 2.8 | 7.9 | 16.2 | 7 | 5 | 5 | 1 | 5 | 14 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.19 |
| RP | Rhodes, A.Rhodes, Arthur >> | 33 | 2002 | L | 65 | 14 | 0 | 1 | 0 | 2.79 | .194 | 0.72 | 6.0 | 1.0 | 9.0 | 9.2 | 6 | 3 | 3 | 1 | 1 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.78 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 56 | 15 | 0 | 2 | 1 | 2.08 | .316 | 1.38 | 6.2 | 6.2 | 9.0 | 13.0 | 9 | 3 | 3 | 1 | 9 | 13 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.08 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 50 | 7 | 0 | 1 | 0 | 2.70 | .286 | 1.20 | 4.5 | 7.5 | 6.0 | 6.2 | 3 | 2 | 2 | 1 | 5 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.33 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 14 | 0 | 1 | 3 | 3.68 | .313 | 1.36 | 6.4 | 6.4 | 12.2 | 14.2 | 10 | 6 | 6 | 1 | 10 | 19 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 3.36 |