| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 19 | 19 | 9 | 2 | 2.99 | .263 | 1.01 | 6.5 | 2.5 | 11.5 | 132.1 | 96 | 45 | 44 | 9 | 37 | 168 | 0 | 0 | 0 | 0 | 14 | 9 | 1 | 2.39 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 86 | 18 | 18 | 8 | 3 | 3.09 | .304 | 1.27 | 6.7 | 4.8 | 10.2 | 96.0 | 71 | 33 | 33 | 6 | 51 | 109 | 1 | 0 | 0 | 1 | 6 | 4 | 1 | 3.26 |
| RP | Sousa, B.Sousa, Bennett >> | 30 | 2025 | L | 82 | 37 | 0 | 1 | 0 | 1.79 | .278 | 1.15 | 7.0 | 3.4 | 10.3 | 50.1 | 39 | 11 | 10 | 4 | 19 | 57 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 2.90 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 77 | 36 | 0 | 6 | 1 | 2.88 | .279 | 1.12 | 7.4 | 2.7 | 6.3 | 50.0 | 41 | 16 | 16 | 5 | 15 | 35 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.92 |
| RP | Santillan, T.Santillan, Tony >> | 28 | 2025 | R | 73 | 31 | 0 | 1 | 3 | 4.45 | .321 | 1.32 | 7.2 | 4.8 | 12.3 | 30.1 | 24 | 20 | 15 | 2 | 16 | 41 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 3.03 |
| RP | Coulombe, D.Coulombe, Daniel >> | 35 | 2025 | L | 64 | 31 | 0 | 1 | 0 | 3.41 | .383 | 1.83 | 10.2 | 6.7 | 13.1 | 31.2 | 35 | 14 | 12 | 5 | 23 | 45 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.52 |
| CL | Miller, M.Miller, Mason >> | 26 | 2025 | R | 98 | 40 | 0 | 2 | 2 | 5.09 | .299 | 1.25 | 8.6 | 2.9 | 11.9 | 40.2 | 38 | 23 | 23 | 6 | 13 | 53 | 0 | 22 | 3 | 0 | 0 | 1 | 2 | 3.35 |
| SP | Burrows, M.Burrows, Mike >> | 25 | 2025 | R | 58 | 6 | 0 | 2 | 0 | 7.36 | .371 | 1.77 | 15.4 | 1.3 | 7.7 | 7.1 | 12 | 6 | 6 | 2 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.43 |