| SP | Falkenberg, C.Falkenberg, Cy >> | 29 | 1909 | R | 92 | 18 | 18 | 8 | 6 | 3.55 | .298 | 1.27 | 8.3 | 3.2 | 4.6 | 126.2 | 116 | 54 | 50 | 7 | 45 | 64 | 3 | 0 | 0 | 0 | 12 | 0 | 4 | 3.78 |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 88 | 18 | 18 | 8 | 6 | 5.37 | .359 | 1.66 | 10.7 | 4.3 | 5.5 | 107.1 | 127 | 72 | 64 | 14 | 51 | 65 | 0 | 0 | 0 | 0 | 9 | 2 | 4 | 4.97 |
| SP | Sabathia, C.Sabathia, CC >> | 25 | 2005 | L | 77 | 17 | 17 | 8 | 6 | 3.56 | .308 | 1.33 | 8.7 | 3.3 | 6.9 | 108.2 | 104 | 50 | 43 | 12 | 40 | 83 | 1 | 0 | 0 | 1 | 10 | 1 | 3 | 4.05 |
| SP | Westbrook, J.Westbrook, Jake # >> | 28 | 2005 | R | 61 | 17 | 17 | 4 | 4 | 4.76 | .320 | 1.38 | 10.2 | 2.3 | 4.9 | 104.0 | 118 | 60 | 55 | 13 | 26 | 57 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.37 |
| SU | Miller, M.Miller, Matt >> | 34 | 2005 | R | 91 | 33 | 0 | 0 | 1 | 2.78 | .281 | 1.14 | 8.2 | 2.3 | 5.3 | 32.1 | 29 | 11 | 10 | 2 | 8 | 19 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.47 |
| RP | Betancourt, R.Betancourt, Rafael >> | 30 | 2005 | R | 89 | 39 | 0 | 5 | 3 | 2.54 | .281 | 1.13 | 8.2 | 2.0 | 9.4 | 46.0 | 42 | 14 | 13 | 4 | 10 | 48 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 2.83 |
| RP | Cabrera, F.Cabrera, Fernando >> | 24 | 2005 | R | 86 | 30 | 0 | 2 | 1 | 2.05 | .224 | 0.86 | 3.9 | 3.9 | 5.7 | 44.0 | 19 | 12 | 10 | 2 | 19 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.61 |
| RP | Guardado, E.Guardado, Eddie >> | 35 | 2005 | L | 75 | 43 | 0 | 1 | 3 | 4.00 | .289 | 1.22 | 9.3 | 1.7 | 8.3 | 27.0 | 28 | 12 | 12 | 3 | 5 | 25 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 3.15 |
| RP | Wickman, B.Wickman, Bob >> | 36 | 2005 | R | 71 | 22 | 0 | 2 | 1 | 0.39 | .247 | 0.99 | 5.9 | 3.1 | 5.9 | 23.1 | 15 | 3 | 1 | 0 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.74 |