| SP | Titcomb, C.Titcomb, Cannonball # >> | 22 | 1888 | L | 51 | 33 | 33 | 14 | 12 | 5.25 | .330 | 1.47 | 10.5 | 2.7 | 5.4 | 231.1 | 270 | 146 | 135 | 22 | 70 | 138 | 8 | 0 | 0 | 0 | 13 | 2 | 19 | 3.98 |
| SP | Anderson, F.Anderson, Fred >> | 32 | 1917 | R | 56 | 31 | 31 | 8 | 5 | 4.45 | .323 | 1.41 | 9.2 | 3.5 | 4.9 | 137.2 | 140 | 72 | 68 | 20 | 54 | 74 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.07 |
| RP | George, B.George, Bill † >> | 23 | 1888 | L | 71 | 79 | 0 | 23 | 3 | 3.65 | .295 | 1.24 | 6.6 | 4.6 | 5.8 | 133.0 | 97 | 61 | 54 | 14 | 68 | 86 | 0 | 1 | 1 | 0 | 0 | 2 | 12 | 4.65 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 83 | 85 | 0 | 3 | 0 | 1.60 | .201 | 0.73 | 3.9 | 2.7 | 8.7 | 95.1 | 41 | 18 | 17 | 6 | 29 | 92 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 2.86 |
| RP | Lopez, J.Lopez, Javier >> | 38 | 2015 | L | 70 | 77 | 0 | 3 | 3 | 4.73 | .313 | 1.34 | 7.4 | 4.8 | 6.2 | 51.1 | 42 | 29 | 27 | 3 | 27 | 35 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.04 |
| RP | Rodríguez, R.Rodríguez, Randy >> | 25 | 2025 | R | 62 | 72 | 0 | 2 | 0 | 3.65 | .240 | 0.95 | 6.1 | 2.4 | 8.2 | 81.1 | 55 | 34 | 33 | 10 | 22 | 74 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.59 |
| RP | Strickland, H.Strickland, Hunter >> | 26 | 2015 | R | 67 | 55 | 0 | 3 | 7 | 4.92 | .328 | 1.43 | 9.5 | 3.5 | 5.3 | 56.2 | 59 | 32 | 31 | 7 | 22 | 33 | 0 | 1 | 6 | 0 | 0 | 2 | 8 | 4.73 |
| SP | Sallee, S.Sallee, Slim >> | 31 | 1916 | L | 46 | 17 | 0 | 2 | 3 | 2.29 | .359 | 1.63 | 12.3 | 2.8 | 2.4 | 19.2 | 26 | 7 | 5 | 2 | 6 | 5 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.95 |
| CL | Romo, S.Romo, Sergio † >> | 25 | 2008 | R | 94 | 71 | 0 | 4 | 2 | 1.81 | .253 | 0.98 | 5.5 | 3.4 | 7.1 | 74.2 | 45 | 20 | 15 | 8 | 28 | 58 | 0 | 40 | 2 | 0 | 0 | 3 | 0 | 4.09 |