| SP | Springs, J.Springs, Jeffrey >> | 29 | 2022 | L | 49 | 27 | 27 | 0 | 11 | 6.99 | .377 | 1.78 | 11.9 | 4.2 | 7.8 | 110.2 | 146 | 90 | 86 | 20 | 51 | 95 | 0 | 0 | 0 | 0 | 0 | 4 | 4 | 5.14 |
| SP | Odorizzi, J.Odorizzi, Jake >> | 25 | 2015 | R | 45 | 27 | 27 | 7 | 16 | 6.87 | .359 | 1.64 | 11.4 | 3.4 | 5.3 | 148.0 | 187 | 115 | 113 | 26 | 56 | 87 | 0 | 0 | 0 | 0 | 8 | 6 | 3 | 5.36 |
| SP | Garza, M.Garza, Matt # >> | 26 | 2009 | R | 41 | 26 | 26 | 7 | 15 | 5.03 | .315 | 1.36 | 8.5 | 3.8 | 7.3 | 171.2 | 161 | 98 | 96 | 20 | 72 | 138 | 0 | 0 | 0 | 0 | 14 | 4 | 2 | 4.24 |
| SP | Kazmir, S.Kazmir, Scott >> | 21 | 2005 | L | 26 | 30 | 25 | 6 | 16 | 5.61 | .343 | 1.55 | 9.5 | 4.4 | 6.7 | 152.1 | 161 | 95 | 95 | 25 | 75 | 113 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 5.19 |
| RP | Balfour, G.Balfour, Grant # >> | 31 | 2008 | R | 80 | 75 | 0 | 2 | 5 | 5.46 | .358 | 1.65 | 8.6 | 6.3 | 9.3 | 87.1 | 83 | 53 | 53 | 10 | 61 | 90 | 0 | 6 | 2 | 0 | 0 | 2 | 3 | 4.60 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 75 | 66 | 0 | 2 | 9 | 4.60 | .301 | 1.27 | 8.7 | 2.7 | 9.1 | 86.0 | 83 | 46 | 44 | 8 | 26 | 87 | 0 | 5 | 3 | 0 | 0 | 2 | 3 | 3.16 |
| RP | Hernandez, R.Hernandez, Roberto >> | 35 | 1999 | R | 12 | 53 | 0 | 2 | 4 | 4.57 | .341 | 1.54 | 9.4 | 4.4 | 6.4 | 65.0 | 68 | 33 | 33 | 9 | 32 | 46 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.91 |