| SP | Brown, M.Brown, Mordecai >> | 33 | 1909 | R | 85 | 20 | 20 | 11 | 6 | 3.99 | .282 | 1.17 | 8.4 | 2.2 | 4.7 | 133.0 | 124 | 65 | 59 | 19 | 32 | 69 | 2 | 0 | 0 | 0 | 13 | 1 | 2 | 4.56 |
| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 98 | 19 | 19 | 14 | 3 | 3.05 | .252 | 1.00 | 7.0 | 2.1 | 9.2 | 138.2 | 107 | 52 | 47 | 11 | 32 | 141 | 3 | 0 | 0 | 0 | 15 | 1 | 5 | 2.71 |
| SP | Alexander, P.Alexander, Pete >> | 32 | 1919 | R | 71 | 19 | 19 | 6 | 6 | 3.65 | .287 | 1.19 | 8.1 | 2.6 | 5.7 | 133.1 | 120 | 66 | 54 | 14 | 39 | 84 | 2 | 0 | 0 | 0 | 11 | 2 | 3 | 4.03 |
| SP | Pfiester, J.Pfiester, Jack >> | 29 | 1907 | L | 60 | 19 | 19 | 4 | 12 | 6.39 | .385 | 1.86 | 12.3 | 4.4 | 5.0 | 100.0 | 137 | 96 | 71 | 19 | 49 | 55 | 0 | 0 | 0 | 0 | 6 | 2 | 3 | 5.90 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 54 | 22 | 19 | 5 | 8 | 5.69 | .369 | 1.73 | 10.9 | 4.6 | 5.7 | 93.1 | 113 | 70 | 59 | 14 | 48 | 59 | 0 | 1 | 0 | 0 | 2 | 3 | 0 | 5.33 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 33 | 2021 | R | 99 | 44 | 0 | 3 | 5 | 1.69 | .260 | 1.05 | 5.4 | 4.3 | 9.4 | 42.2 | 25 | 12 | 8 | 3 | 20 | 44 | 0 | 27 | 1 | 0 | 0 | 0 | 4 | 3.26 |
| RP | Ramsdell, W.Ramsdell, Willie >> | 36 | 1952 | R | 63 | 48 | 0 | 3 | 2 | 5.54 | .339 | 1.53 | 9.0 | 4.7 | 4.7 | 78.0 | 78 | 60 | 48 | 12 | 41 | 41 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 5.56 |
| RP | Tepera, R.Tepera, Ryan >> | 33 | 2021 | R | 91 | 36 | 0 | 3 | 2 | 2.82 | .280 | 1.14 | 7.0 | 3.5 | 9.2 | 44.2 | 34 | 16 | 14 | 1 | 17 | 45 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2.48 |