| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 69 | 34 | 34 | 9 | 14 | 4.13 | .302 | 1.28 | 8.3 | 3.2 | 8.4 | 209.0 | 193 | 97 | 96 | 31 | 74 | 194 | 0 | 0 | 0 | 0 | 18 | 4 | 4 | 4.19 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 65 | 33 | 33 | 2 | 21 | 6.15 | .351 | 1.59 | 9.6 | 4.8 | 8.6 | 177.0 | 188 | 127 | 121 | 19 | 94 | 170 | 1 | 0 | 0 | 0 | 14 | 5 | 6 | 4.15 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 64 | 32 | 32 | 8 | 16 | 5.40 | .330 | 1.47 | 9.4 | 3.8 | 8.6 | 188.1 | 197 | 115 | 113 | 32 | 80 | 179 | 2 | 0 | 0 | 0 | 14 | 1 | 10 | 4.60 |
| SP | Paddack, C.Paddack, Chris # >> | 23 | 2019 | R | 59 | 32 | 32 | 10 | 9 | 4.62 | .300 | 1.27 | 8.8 | 2.7 | 8.7 | 179.1 | 175 | 96 | 92 | 30 | 53 | 173 | 0 | 0 | 0 | 0 | 13 | 3 | 5 | 4.18 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 79 | 0 | 5 | 2 | 2.23 | .266 | 1.09 | 6.1 | 3.7 | 7.5 | 93.0 | 63 | 24 | 23 | 7 | 38 | 77 | 0 | 9 | 4 | 0 | 0 | 0 | 1 | 3.55 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 92 | 63 | 0 | 2 | 6 | 3.97 | .301 | 1.28 | 7.9 | 3.6 | 8.5 | 68.0 | 60 | 34 | 30 | 8 | 27 | 64 | 0 | 6 | 1 | 0 | 0 | 1 | 6 | 3.88 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 75 | 50 | 0 | 3 | 3 | 4.91 | .345 | 1.58 | 11.6 | 2.6 | 8.8 | 51.1 | 66 | 32 | 28 | 9 | 15 | 50 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 68 | 26 | 0 | 4 | 4 | 3.99 | .313 | 1.36 | 9.3 | 3.1 | 7.1 | 29.1 | 30 | 15 | 13 | 5 | 10 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.69 |
| RP | Andersen, L.Andersen, Larry >> | 39 | 1992 | R | 49 | 32 | 0 | 0 | 2 | 4.58 | .329 | 1.44 | 9.0 | 4.1 | 10.3 | 35.1 | 35 | 20 | 18 | 7 | 16 | 40 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.77 |
| SP | Musgrove, J.Musgrove, Joseph >> | 28 | 2021 | R | 45 | 25 | 0 | 2 | 4 | 4.90 | .318 | 1.37 | 8.5 | 3.9 | 7.6 | 115.2 | 108 | 68 | 63 | 20 | 50 | 97 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 4.98 |