| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 19 | 19 | 10 | 7 | 3.67 | .293 | 1.21 | 8.2 | 2.7 | 7.8 | 137.1 | 125 | 57 | 56 | 8 | 41 | 119 | 3 | 0 | 0 | 0 | 12 | 5 | 3 | 3.03 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 78 | 18 | 18 | 7 | 9 | 5.03 | .319 | 1.40 | 8.0 | 4.7 | 4.7 | 120.0 | 106 | 70 | 67 | 9 | 62 | 63 | 3 | 0 | 0 | 0 | 9 | 1 | 4 | 4.50 |
| SP | Buchholz, C.Buchholz, Clay >> | 29 | 2013 | R | 72 | 18 | 18 | 4 | 9 | 4.45 | .310 | 1.32 | 8.5 | 3.5 | 6.0 | 119.1 | 112 | 61 | 59 | 15 | 46 | 79 | 0 | 0 | 0 | 0 | 10 | 3 | 1 | 4.55 |
| SP | Hughson, T.Hughson, Tex >> | 30 | 1946 | R | 44 | 17 | 17 | 5 | 8 | 5.40 | .331 | 1.47 | 10.9 | 2.4 | 4.8 | 111.2 | 135 | 67 | 67 | 8 | 29 | 59 | 1 | 0 | 0 | 0 | 5 | 2 | 1 | 3.71 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 99 | 29 | 0 | 0 | 2 | 3.42 | .313 | 1.33 | 6.6 | 5.5 | 10.7 | 26.1 | 19 | 10 | 10 | 3 | 16 | 31 | 0 | 22 | 4 | 0 | 0 | 1 | 1 | 4.08 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 82 | 44 | 0 | 2 | 1 | 6.57 | .308 | 1.34 | 6.4 | 6.0 | 8.6 | 24.2 | 17 | 19 | 18 | 7 | 16 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 6.88 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 31 | 2011 | R | 58 | 30 | 0 | 1 | 2 | 4.35 | .380 | 1.84 | 13.5 | 3.6 | 8.6 | 20.2 | 30 | 10 | 10 | 1 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.95 |
| RP | Embree, A.Embree, Alan >> | 32 | 2002 | L | 48 | 29 | 0 | 0 | 3 | 1.47 | .295 | 1.20 | 6.0 | 5.0 | 6.0 | 18.1 | 12 | 4 | 3 | 2 | 10 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.94 |
| RP | Brice, A.Brice, Austin >> | 27 | 2019 | R | 30 | 17 | 0 | 1 | 0 | 3.45 | .319 | 1.40 | 10.2 | 3.0 | 7.8 | 15.2 | 17 | 6 | 6 | 0 | 5 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.27 |
| RP | Stratton, C.Stratton, Chris >> | 32 | 2023 | R | 34 | 13 | 0 | 0 | 0 | 4.63 | .286 | 1.20 | 10.6 | 0.8 | 2.5 | 11.2 | 13 | 6 | 6 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.09 |
| SP | Weaver, J.Weaver, Jered >> | 33 | 2015 | R | 28 | 8 | 0 | 0 | 1 | 9.59 | .411 | 2.05 | 15.8 | 2.9 | 5.8 | 25.1 | 44 | 27 | 27 | 7 | 8 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.44 |