| RP | Affeldt, J.Affeldt, Jeremy | 36 | 2015 | L | 2 | 2 | 5.86 | .331 | .410 | 1.63 | 11.1 | 3.6 | 5.4 | 35 | 43 | 6 | 14 | 21 | 0 | 0 | 1 | 23 | -0.78 | C |
| RP | Affeldt, J.Affeldt, Jeremy | 36 | 2015 | L | 2 | 2 | 5.86 | .331 | .410 | 1.63 | 11.1 | 3.6 | 5.4 | 35 | 43 | 6 | 14 | 21 | 0 | 0 | 1 | 23 | -0.78 | C |
| RP | Affeldt, J.Affeldt, Jeremy | 36 | 2015 | L | 2 | 2 | 5.86 | .331 | .410 | 1.63 | 11.1 | 3.6 | 5.4 | 35 | 43 | 6 | 14 | 21 | 0 | 0 | 1 | 23 | -0.78 | C |
| SP | Blanton, J.Blanton, Joe | 33 | 2013 | R | 2 | 14 | 6.04 | .345 | .410 | 1.62 | 12.3 | 2.3 | 7.4 | 132 | 180 | 29 | 34 | 108 | 0 | 0 | 9 | 84 | -1.92 | C |
| SP | Buchholz, C.Buchholz, Clay | 32 | 2016 | R | 8 | 10 | 4.78 | .302 | .360 | 1.33 | 8.4 | 3.6 | 6.0 | 139 | 130 | 21 | 55 | 93 | 0 | 0 | 1 | 68 | +0.15 | C |
| SP | Carpenter, C.Carpenter, Chris | 27 | 2002 | R | 4 | 5 | 5.28 | .336 | .400 | 1.59 | 11.0 | 3.3 | 5.5 | 73 | 89 | 11 | 27 | 45 | 1 | 0 | 3 | 99 | +0.49 | C |
| RP | Cassidy, S.Cassidy, Scott | 27 | 2002 | R | 1 | 4 | 5.73 | .288 | .350 | 1.27 | 7.1 | 4.4 | 6.5 | 66 | 52 | 12 | 32 | 48 | 0 | 0 | 2 | 23 | -0.16 | C |
| RP | File, B.File, Bob | 27 | 2004 | R | 1 | 0 | 4.81 | .343 | .420 | 1.73 | 12.3 | 3.3 | 4.1 | 33 | 45 | 4 | 12 | 15 | 0 | 0 | 1 | 27 | +0.09 | C |
| RP | Frederick, K.Frederick, Kevin | 28 | 2004 | R | 0 | 2 | 6.59 | .338 | .420 | 1.71 | 10.3 | 5.1 | 7.1 | 28 | 32 | 4 | 16 | 22 | 0 | 0 | 0 | 26 | -0.26 | C |
| RP | Garcia, Y.Garcia, Yimi | 24 | 2015 | R | 3 | 5 | 3.34 | .233 | .300 | 0.96 | 7.1 | 1.6 | 10.9 | 56 | 44 | 8 | 10 | 68 | 0 | 1 | 1 | 23 | +0.45 | C |
| RP | Gonzalez, V.Gonzalez, Victor | 25 | 2021 | L | 3 | 1 | 3.57 | .307 | .380 | 1.46 | 8.2 | 4.9 | 8.5 | 35 | 32 | 3 | 19 | 33 | 0 | 1 | 1 | 23 | +0.5 | C |
| RP | Hawkins, L.Hawkins, LaTroy | 43 | 2015 | R | 3 | 1 | 3.26 | .291 | .360 | 1.34 | 10.4 | 1.7 | 8.1 | 38 | 44 | 4 | 7 | 34 | 0 | 3 | 1 | 23 | +0.59 | C |
| RP | Hawkins, L.Hawkins, LaTroy | 43 | 2015 | R | 3 | 1 | 3.26 | .291 | .360 | 1.34 | 10.4 | 1.7 | 8.1 | 38 | 44 | 4 | 7 | 34 | 0 | 3 | 1 | 23 | +0.59 | C |
| RP | Hawkins, L.Hawkins, LaTroy | 43 | 2015 | R | 3 | 1 | 3.26 | .291 | .360 | 1.34 | 10.4 | 1.7 | 8.1 | 38 | 44 | 4 | 7 | 34 | 0 | 3 | 1 | 23 | +0.59 | C |
| SP | Hentgen, P.Hentgen, Pat | 36 | 2004 | R | 2 | 9 | 6.95 | .346 | .410 | 1.65 | 10.1 | 4.7 | 3.7 | 80 | 90 | 16 | 42 | 33 | 0 | 0 | 1 | 80 | -1.23 | C |
| RP | Koch, B.Koch, Billy | 30 | 2004 | R | 2 | 3 | 4.41 | .340 | .410 | 1.65 | 8.3 | 6.6 | 9.2 | 49 | 45 | 6 | 36 | 50 | 0 | 8 | 5 | 23 | +0.05 | C |
| RP | Machi, J.Machi, Jean | 33 | 2015 | R | 2 | 0 | 5.12 | .306 | .370 | 1.40 | 9.2 | 3.4 | 6.5 | 58 | 59 | 8 | 22 | 42 | 0 | 4 | 3 | 23 | -0.46 | C |
| RP | Maddox, A.Maddox, Austin | 26 | 2017 | R | 0 | 0 | 0.52 | .197 | .280 | 0.88 | 6.9 | 1.1 | 7.4 | 17 | 13 | 1 | 2 | 14 | 0 | 0 | 0 | 26 | +0.66 | C |
| SP | Maeda, K.Maeda, Kenta | 33 | 2021 | R | 6 | 5 | 4.66 | .296 | .360 | 1.30 | 9.0 | 2.7 | 9.6 | 106 | 106 | 16 | 32 | 113 | 0 | 0 | 3 | 90 | +0.3 | C |
| SP | Masterson, J.Masterson, Justin | 30 | 2015 | R | 4 | 2 | 5.61 | .337 | .400 | 1.61 | 10.4 | 4.1 | 7.5 | 59 | 68 | 7 | 27 | 49 | 0 | 0 | 7 | 60 | -0.26 | C |
| RP | Mujica, E.Mujica, Edward | 31 | 2015 | R | 3 | 5 | 4.75 | .281 | .350 | 1.26 | 10.0 | 1.3 | 5.7 | 47 | 52 | 10 | 7 | 30 | 0 | 1 | 1 | 23 | -0.43 | C |
| RP | Nakamura, M.Nakamura, Mike | 28 | 2004 | R | 0 | 3 | 7.36 | .286 | .370 | 1.36 | 9.7 | 2.5 | 8.6 | 25 | 27 | 7 | 7 | 24 | 0 | 0 | 3 | 26 | -0.68 | C |
| SP | Nolasco, R.Nolasco, Ricky | 35 | 2017 | R | 6 | 15 | 4.92 | .322 | .380 | 1.45 | 10.2 | 2.9 | 7.1 | 181 | 205 | 35 | 58 | 143 | 1 | 0 | 4 | 97 | +0.71 | C |
| SP | Owens, H.Owens, Henry | 24 | 2016 | L | 0 | 2 | 6.95 | .361 | .450 | 1.95 | 9.4 | 8.2 | 8.6 | 22 | 23 | 5 | 20 | 21 | 0 | 0 | 3 | 79 | -0.41 | C |
| RP | Papelbon, J.Papelbon, Jonathan | 36 | 2016 | R | 2 | 4 | 4.37 | .307 | .380 | 1.46 | 9.5 | 3.6 | 8.0 | 35 | 37 | 3 | 14 | 31 | 0 | 19 | 1 | 23 | +0.02 | C |
| RP | Sadler, C.Sadler, Casey | 28 | 2019 | R | 4 | 0 | 2.14 | .267 | .340 | 1.17 | 8.0 | 2.5 | 6.1 | 46 | 41 | 5 | 13 | 31 | 0 | 1 | 0 | 28 | +0.83 | C |
| RP | Sadler, C.Sadler, Casey | 30 | 2021 | R | 0 | 1 | 0.67 | .182 | .250 | 0.73 | 4.3 | 2.3 | 8.3 | 40 | 19 | 1 | 10 | 37 | 0 | 0 | 2 | 23 | +2.1 | C |
| RP | Scott, R.Scott, Robby | 27 | 2017 | L | 2 | 1 | 3.79 | .233 | .310 | 1.00 | 5.7 | 3.3 | 8.0 | 35 | 22 | 7 | 13 | 31 | 0 | 0 | 3 | 23 | +0.49 | C |