| SP | Clevinger, M.Clevinger, Mike $$ | Indians | R | 198.0 | 37 | 37 | 25 | 9 | 2.84 | .279 | 1.15 | 7.0 | 3.4 | 10.0 | 256.2 | 199 | 85 | 81 | 26 | 96 | 284 | 5 | 0 | 0 | 2 | 0 | 3 | 3 | 3.26 |
| SP | Bauer, T.Bauer, Trevor $$ | Indians | R | 187.0 | 38 | 38 | 22 | 10 | 3.23 | .256 | 1.00 | 6.4 | 2.7 | 10.4 | 287.0 | 203 | 104 | 103 | 29 | 85 | 331 | 12 | 0 | 0 | 2 | 0 | 8 | 7 | 2.98 |
| SP | Verlander, J.Verlander, Justin $$ | Astros | R | 181.0 | 33 | 33 | 18 | 10 | 2.22 | .230 | 0.86 | 6.2 | 1.6 | 11.3 | 243.0 | 167 | 61 | 60 | 17 | 43 | 304 | 6 | 0 | 0 | 5 | 0 | 8 | 6 | 2.04 |
| SP | Worley, V.Worley, Vance $$ | Indians | R | 156.0 | 35 | 35 | 21 | 2 | 3.27 | .290 | 1.21 | 7.6 | 3.2 | 8.0 | 212.0 | 180 | 83 | 77 | 25 | 76 | 188 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 3.89 |
| CL | Castillo, D.Castillo, Diego $$ | Rays | R | 149.5 | 74 | 0 | 6 | 3 | 1.67 | .207 | 0.76 | 4.4 | 2.6 | 12.3 | 91.2 | 44 | 17 | 17 | 7 | 26 | 124 | 0 | 35 | 5 | 0 | 0 | 2 | 4 | 2.20 |
| SP | Paxton, J.Paxton, James $$ | Rays | L | 139.0 | 36 | 36 | 17 | 6 | 3.14 | .282 | 1.15 | 7.8 | 2.5 | 10.6 | 217.2 | 189 | 80 | 76 | 12 | 61 | 256 | 1 | 0 | 0 | 0 | 0 | 6 | 10 | 2.29 |