| SP | Valenzuela, F.Valenzuela, Fernando † | Dodgers | L | 172.0 | 34 | 34 | 17 | 11 | 2.14 | .247 | 0.98 | 7.0 | 1.8 | 6.6 | 264.2 | 206 | 76 | 63 | 17 | 54 | 194 | 10 | 0 | 0 | 0 | 28 | 1 | 1 | 2.99 |
| SP | Larson, D.Larson, Dan † # | Astros | R | 165.0 | 35 | 35 | 20 | 13 | 2.91 | .266 | 1.08 | 7.4 | 2.3 | 4.3 | 278.0 | 230 | 95 | 90 | 19 | 70 | 132 | 13 | 0 | 0 | 3 | 23 | 2 | 5 | 3.72 |
| SP | Hammaker, A.Hammaker, Atlee | Dodgers | L | 148.0 | 34 | 34 | 17 | 16 | 2.82 | .242 | 0.95 | 7.1 | 1.5 | 4.8 | 268.0 | 210 | 90 | 84 | 16 | 45 | 143 | 19 | 0 | 0 | 1 | 24 | 1 | 2 | 3.22 |
| CL | Solano, J.Solano, Julio † | Astros | R | 148.0 | 57 | 0 | 0 | 0 | 1.25 | .206 | 0.78 | 4.1 | 3.0 | 5.2 | 57.2 | 26 | 8 | 8 | 4 | 19 | 33 | 0 | 50 | 2 | 0 | 0 | 0 | 0 | 3.75 |
| SP | Gooden, D.Gooden, Dwight † | Mets | R | 140.0 | 34 | 34 | 17 | 12 | 2.90 | .277 | 1.14 | 7.6 | 2.7 | 8.8 | 239.0 | 201 | 91 | 77 | 18 | 72 | 234 | 5 | 0 | 0 | 0 | 25 | 2 | 5 | 2.95 |
| SP | Russell, J.Russell, Jeff # | Reds | R | 138.0 | 36 | 36 | 20 | 11 | 4.00 | .289 | 1.22 | 8.8 | 2.2 | 5.3 | 265.2 | 259 | 127 | 118 | 31 | 64 | 156 | 12 | 0 | 0 | 6 | 19 | 1 | 4 | 4.08 |
| SP | Righetti, D.Righetti, Dave | Yankees | L | 138.0 | 33 | 33 | 14 | 10 | 2.78 | .229 | 0.89 | 6.3 | 1.7 | 6.5 | 252.1 | 176 | 79 | 78 | 21 | 48 | 182 | 10 | 0 | 0 | 1 | 26 | 1 | 0 | 3.22 |