| SP | McLain, D.McLain, Denny † | Cats | R | 162.0 | 29 | 29 | 17 | 8 | 2.59 | .262 | 1.04 | 6.4 | 2.9 | 5.5 | 229.1 | 164 | 72 | 66 | 13 | 75 | 139 | 17 | 0 | 0 | 4 | 22 | 5 | 1 | 3.57 |
| SP | Halladay, R.Halladay, Roy † # | Blue Jays | R | 142.0 | 28 | 28 | 17 | 5 | 3.00 | .278 | 1.14 | 8.4 | 1.9 | 5.1 | 222.1 | 208 | 81 | 74 | 17 | 46 | 125 | 6 | 0 | 0 | 2 | 17 | 3 | 3 | 3.53 |
| SP | Skubal, T.Skubal, Tarik † | Cats | L | 132.0 | 28 | 28 | 16 | 4 | 2.74 | .284 | 1.16 | 7.8 | 2.7 | 8.7 | 174.1 | 150 | 62 | 53 | 9 | 53 | 169 | 2 | 0 | 0 | 1 | 21 | 4 | 1 | 2.71 |
| CL | Kimbrel, C.Kimbrel, Craig † | Braves | R | 109.5 | 52 | 0 | 8 | 6 | 2.04 | .232 | 0.91 | 6.0 | 2.2 | 9.6 | 57.1 | 38 | 17 | 13 | 3 | 14 | 61 | 0 | 25 | 4 | 0 | 0 | 0 | 4 | 2.28 |
| SP | Scherzer, M.Scherzer, Max † | Metropolitans | R | 106.0 | 28 | 28 | 13 | 7 | 3.30 | .281 | 1.13 | 8.2 | 2.0 | 8.7 | 188.0 | 172 | 71 | 69 | 11 | 41 | 182 | 3 | 0 | 0 | 2 | 19 | 7 | 1 | 2.59 |