| SP | Cortes Jr., N.Cortes Jr., Nestor † | Yankees | L | 141.0 | 27 | 27 | 16 | 2 | 2.35 | .256 | 1.01 | 6.6 | 2.5 | 8.6 | 176.0 | 129 | 51 | 46 | 13 | 49 | 168 | 0 | 0 | 0 | 0 | 19 | 4 | 1 | 2.95 |
| SP | Righetti, D.Righetti, Dave † | Yankees | L | 122.0 | 26 | 26 | 18 | 4 | 3.66 | .299 | 1.24 | 7.5 | 3.7 | 6.7 | 191.2 | 159 | 85 | 78 | 19 | 79 | 143 | 1 | 0 | 0 | 0 | 17 | 7 | 4 | 4.15 |
| CL | Chapman, A.Chapman, Aroldis † | Reds | L | 114.5 | 72 | 0 | 7 | 6 | 3.29 | .290 | 1.18 | 6.6 | 4.1 | 10.6 | 79.1 | 58 | 34 | 29 | 8 | 36 | 93 | 0 | 29 | 2 | 0 | 0 | 3 | 4 | 3.44 |
| CL | Gossage, R.Gossage, Rich † | Yankees | R | 110.5 | 57 | 0 | 4 | 2 | 4.25 | .292 | 1.24 | 6.9 | 4.3 | 9.0 | 55.0 | 42 | 26 | 26 | 5 | 26 | 55 | 0 | 37 | 6 | 0 | 0 | 0 | 0 | 3.60 |
| SP | Greinke, Z.Greinke, Zack † # | Diamondbacks | R | 91.0 | 26 | 26 | 12 | 5 | 3.58 | .275 | 1.12 | 8.1 | 1.9 | 6.9 | 171.0 | 154 | 74 | 68 | 22 | 37 | 132 | 2 | 0 | 0 | 1 | 15 | 4 | 5 | 3.85 |
| CL | Hernandez, W.Hernandez, Willie # | Wildcats | L | 85.5 | 51 | 0 | 4 | 7 | 3.92 | .295 | 1.24 | 8.2 | 3.0 | 5.8 | 57.1 | 52 | 25 | 25 | 6 | 19 | 37 | 0 | 29 | 2 | 0 | 0 | 1 | 0 | 4.12 |