| RP | Takatsu, S.Takatsu, Shingo † | Red Sox | R | 120.0 | 70 | 0 | 6 | 5 | 1.72 | .222 | 0.82 | 5.0 | 2.4 | 6.9 | 89.0 | 49 | 21 | 17 | 6 | 24 | 68 | 0 | 26 | 2 | 0 | 0 | 3 | 0 | 3.26 |
| RP | Carrasco, H.Carrasco, Hector † | Prospects | R | 114.0 | 103 | 0 | 15 | 7 | 3.23 | .253 | 1.00 | 6.7 | 2.3 | 6.9 | 189.2 | 140 | 76 | 68 | 20 | 49 | 144 | 0 | 2 | 1 | 0 | 0 | 4 | 4 | 3.69 |
| CL | Politte, C.Politte, Cliff † | Bulls | R | 104.0 | 51 | 0 | 3 | 6 | 2.40 | .244 | 0.97 | 6.4 | 2.4 | 9.0 | 48.2 | 34 | 16 | 13 | 5 | 13 | 48 | 0 | 34 | 1 | 0 | 0 | 0 | 1 | 3.17 |
| CL | Gonzalez, M.Gonzalez, Mike | Giants | L | 102.0 | 64 | 0 | 1 | 1 | 3.75 | .283 | 1.18 | 8.3 | 2.4 | 10.1 | 60.0 | 55 | 26 | 25 | 3 | 16 | 67 | 0 | 38 | 9 | 0 | 0 | 0 | 3 | 2.22 |
| CL | Papelbon, J.Papelbon, Jonathan † | Millionaires | R | 99.0 | 60 | 0 | 3 | 3 | 3.28 | .259 | 1.00 | 6.5 | 2.6 | 8.7 | 90.2 | 65 | 34 | 33 | 13 | 26 | 87 | 0 | 28 | 4 | 0 | 0 | 4 | 4 | 3.94 |
| RP | Soriano, R.Soriano, Rafael | Cardinals | R | 97.0 | 70 | 0 | 7 | 1 | 1.77 | .225 | 0.84 | 4.9 | 2.7 | 8.8 | 91.2 | 50 | 20 | 18 | 5 | 27 | 89 | 0 | 10 | 0 | 0 | 0 | 3 | 0 | 2.75 |