| SP | Miller, J.Miller, Justin † + | Devil Rays | R | 139.0 | 23 | 23 | 15 | 2 | 2.35 | .253 | 0.97 | 6.6 | 2.1 | 7.3 | 176.1 | 129 | 48 | 46 | 11 | 42 | 142 | 5 | 0 | 0 | 1 | 17 | 8 | 4 | 3.05 |
| SP | Waechter, D.Waechter, Doug † | Devil Rays | R | 137.0 | 24 | 24 | 15 | 5 | 2.26 | .231 | 0.88 | 5.4 | 2.5 | 9.0 | 183.0 | 110 | 49 | 46 | 11 | 51 | 184 | 2 | 0 | 0 | 0 | 20 | 4 | 0 | 2.67 |
| CL | Zambrano, V.Zambrano, Victor † | Devil Rays | R | 115.0 | 52 | 0 | 4 | 5 | 3.55 | .277 | 1.11 | 6.7 | 3.4 | 7.9 | 58.1 | 43 | 24 | 23 | 7 | 22 | 51 | 0 | 38 | 3 | 0 | 0 | 2 | 3 | 4.05 |
| CL | Soriano, R.Soriano, Rafael † | Mariners | R | 107.5 | 41 | 0 | 1 | 0 | 1.42 | .224 | 0.82 | 6.2 | 1.2 | 10.9 | 38.0 | 26 | 8 | 6 | 2 | 5 | 46 | 0 | 35 | 3 | 0 | 0 | 2 | 0 | 1.82 |
| SP | Maddux, G.Maddux, Greg † # | Angels | R | 99.0 | 23 | 23 | 12 | 8 | 3.00 | .286 | 1.17 | 8.0 | 2.6 | 6.2 | 168.0 | 149 | 58 | 56 | 17 | 48 | 116 | 6 | 0 | 0 | 3 | 16 | 5 | 1 | 3.88 |
| SP | Hernandez, F.Hernandez, Felix † | Mariners | R | 96.0 | 22 | 22 | 13 | 6 | 3.18 | .274 | 1.12 | 7.8 | 2.3 | 6.0 | 158.1 | 137 | 59 | 56 | 18 | 41 | 106 | 2 | 0 | 0 | 2 | 14 | 1 | 3 | 3.94 |
| SP | Haynes, J.Haynes, Jimmy + | Orioles | R | 92.0 | 23 | 23 | 11 | 11 | 3.44 | .280 | 1.15 | 5.8 | 4.6 | 9.0 | 180.1 | 116 | 70 | 69 | 6 | 92 | 180 | 11 | 0 | 0 | 2 | 13 | 2 | 0 | 3.00 |